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Published in 2019 at "Molecular Diversity"
DOI: 10.1007/s11030-019-09968-x
Abstract: The new multicomponent reaction (MCR) has been found: one-pot selective and efficient formation of the new 5-(4-hydroxy-2-oxo-1,2-dihydropyridin-3-yl)-substituted 5H-chromeno[2,3-b]pyridines in 61–97% yields directly from simple and easily available salicylaldehydes, malononitrile dimer and 4-hydroxypyridine-2(1H)-ones in small amount…
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Keywords:
hydroxypyridine ones;
pyridine;
dimer hydroxypyridine;
chromeno pyridine ... See more keywords
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Published in 2018 at "Russian Chemical Bulletin"
DOI: 10.1007/s11172-018-2278-1
Abstract: A new multicomponent reaction, namely, a one-pot transformation of salicylaldehydes, 2-aminoprop-1-ene-1,1,3-tricarbonitrile, and 2-pyrazolin-5-ones in the presence of triethylamine as the catalyst in a minimum amount of propanol leads to the previously unknown substituted 2,4-diamino-5-(5-hydroxy-3-methyl-1H-pyrazol-4-yl)-5H-chromeno [2,3-b]-…
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Keywords:
chromeno pyridine;
substituted diamino;
transformation salicylaldehydes;
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Published in 2018 at "Synlett"
DOI: 10.1055/s-0036-1591535
Abstract: This work discloses a novel and efficient protocol for the construction of functionalized chromeno[3,4-c]pyridine derivatives from the Blaise reaction intermediates and 3-cyanocoumarins through a CuCl2-catalyzed sequential Michael addition/intramolecular cyclization/oxidative aromatization reaction. This new method shows…
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Keywords:
reaction intermediates;
blaise reaction;
functionalized chromeno;
chromeno pyridine ... See more keywords
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Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24097724
Abstract: About twenty molecules sharing 1H-chromeno[3,2-c]pyridine as the scaffold and differing in the degree of saturation of the pyridine ring, oxidation at C10, 1-phenylethynyl at C1 and 1H-indol-3-yl fragments at C10, as well as a few…
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Keywords:
chromeno pyridine;
pyridine;
activity;
chemical biological ... See more keywords