Access to Chiral Chromenones through Organocatalyzed Mannich/Annulation Sequence.
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DOI: 10.1021/acs.orglett.1c03010
Abstract: Herein we report an efficient and practical method to access chiral chromenones bearing one α-amino stereogenic center in the β position of the carbonyl group. The quinine-derived squaramide could efficiently promote Mannich/cycloketalization/dehydration tandem reactions between… read more here.
Keywords: organocatalyzed mannich; mannich annulation; access chiral; chromenones organocatalyzed ... See more keywords