Articles with "chromodomain" as a keyword



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A Potent, Selective CBX2 Chromodomain Ligand and Its Cellular Activity During Prostate Cancer Neuroendocrine Differentiation

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Published in 2021 at "ChemBioChem"

DOI: 10.1002/cbic.202100118

Abstract: Polycomb group (PcG) proteins are epigenetic regulators that facilitate both embryonic development and cancer progression. PcG proteins form Polycomb repressive complexes 1 and 2 (PRC1 and PRC2). PRC2 trimethylates histone H3 lysine 27 (H3K27me3), a… read more here.

Keywords: prostate cancer; selective cbx2; cancer; cbx2 ... See more keywords