CHD4 acts as a critical regulator in the survival of spermatogonial stem cells in mice
Sign Up to like & getrecommendations! Published in 2022 at "Biology of Reproduction"
DOI: 10.1093/biolre/ioac162
Abstract: Abstract Spermatogenesis is sustained by homeostatic balance between the self-renewal and differentiation of spermatogonial stem cells, which is dependent on the strict regulation of transcription factor and chromatin modulator gene expression. Chromodomain helicase DNA-binding protein… read more here.
Keywords: chromodomain helicase; spermatogonial stem; helicase dna; dna binding ... See more keywords
A Chromodomain-Helicase-DNA-Binding Factor Functions in Chromatin Modification and Gene Regulation1[OPEN]
Sign Up to like & getrecommendations! Published in 2020 at "Plant Physiology"
DOI: 10.1104/pp.20.00453
Abstract: The chromodomain-helicase-DNA-binding factor CHR729 regulates nucleosome positioning and histone modification to control the expression of poised genes in rice. Proteins in the Chromodomain-Helicase/ATPase-DNA-binding domain (CHD) family are divided into three groups. The function of group… read more here.
Keywords: expression; dna binding; gene; modification ... See more keywords
The possible impact of DNA‐binding chromodomain‐helicase 5 polymorphisms on male infertility: A case–control study
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Obstetrics and Gynaecology Research"
DOI: 10.1111/jog.15560
Abstract: Chromodomain‐helicase 5 (CHD5) is a conventional tumor‐suppressing gene in many tumors. The CHD5 gene, as a key factor in the chromatin density process during sperm maturation, can affect the risk of infertility. This study aimed… read more here.
Keywords: chromodomain helicase; infertility; possible impact; male infertility ... See more keywords
A spontaneous missense mutation in the chromodomain helicase DNA‐binding protein 8 (CHD8) gene: a novel association with congenital myasthenic syndrome
Sign Up to like & getrecommendations! Published in 2020 at "Neuropathology and Applied Neurobiology"
DOI: 10.1111/nan.12617
Abstract: Congenital myasthenic syndromes (CMS) are characterized by muscle weakness, ptosis and episodic apnoea. Mutations affect integral protein components of the neuromuscular junction (NMJ). Here we searched for the genetic basis of CMS in female monozygotic… read more here.
Keywords: protein; spontaneous missense; congenital myasthenic; mutation chromodomain ... See more keywords
The role of chromodomain helicase DNA binding protein 1 (CHD1) in promoting an invasive prostate cancer phenotype
Sign Up to like & getrecommendations! Published in 2021 at "Therapeutic Advances in Urology"
DOI: 10.1177/17562872211022462
Abstract: Background: Prostate cancer (PCa) phenotypes vary from indolent to aggressive. Molecular subtyping may be useful in predicting aggressive cancers and directing therapy. One such subtype involving deletions of chromodomain helicase DNA binding protein 1 (CHD1),… read more here.
Keywords: prostate; helicase dna; chd1; prostate cancer ... See more keywords