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   Articles with "chromogranin" as a keyword



Glycosylated Chromogranin A: Potential Role in the Pathogenesis of Heart Failure

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recommendations! Published in 2017 at "Current Heart Failure Reports"

DOI: 10.1007/s11897-017-0360-x

Abstract: Purpose of ReviewEndocrine and paracrine factors influence the cardiovascular system and the heart by a number of different mechanisms. The chromogranin-secretogranin (granin) proteins seem to represent a new family of proteins that exerts both direct… read more here.

Keywords: chromogranin; heart; granin protein; heart failure ... See more keywords

Chromogranin A and catestatin regulate pancreatic islet homeostasis, endocrine function, and neurotransmitter signaling

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recommendations! Published in 2025 at "Communications Biology"

DOI: 10.1038/s42003-025-09135-z

Abstract: Chromogranin A (CgA), a neuroendocrine pro-hormone, is proteolytically cleaved into bioactive peptides, most notably catestatin (CST) and pancreastatin (PST), which exert opposing effects on metabolic and inflammatory processes. Using CgA- and CST knockout (KO) mice,… read more here.

Keywords: homeostasis; chromogranin; function; endocrine function ... See more keywords

Plasma Chromogranin A as a Prognostic Marker in Pancreatic Ductal Adenocarcinoma

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recommendations! Published in 2019 at "Pancreas"

DOI: 10.1097/mpa.0000000000001319

Abstract: Objectives Neuroendocrine differentiation in pancreatic ductal adenocarcinoma (PDAC) is known, but its clinical significance still remains uncertain. The clinical role of chromogranin A (CgA), a marker of neuroendocrine tumor, was evaluated in patients with PDAC.… read more here.

Keywords: cga; high cga; pancreatic ductal; ductal adenocarcinoma ... See more keywords

Role of Chromogranin A in the Diagnosis and Follow-up of Neuroendocrine Tumors

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recommendations! Published in 2022 at "Pancreas"

DOI: 10.1097/mpa.0000000000002132

Abstract: Objective The aim of this study was to assess the utility of serum chromogranin A (CgA) along the clinical pathway of patients with neuroendocrine tumors (NETs). Methods A retrospective review of medical records was conducted… read more here.

Keywords: cga; diagnosis follow; neuroendocrine tumors; chromogranin diagnosis ... See more keywords

Clinical utility of chromogranin A for the surveillance of succinate dehydrogenase B- and succinate dehydrogenase D-related paraganglioma

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recommendations! Published in 2019 at "Annals of Clinical Biochemistry"

DOI: 10.1177/0004563218811865

Abstract: Background Patients with mutations of succinate dehydrogenase B (SDHB) and succinate dehydrogenase D (SDHD) are at high risk of paraganglioma necessitating surveillance. Chromogranin A has been proposed as a biochemical marker of paraganglioma. We sought… read more here.

Keywords: dehydrogenase; chromogranin; surveillance; paraganglioma ... See more keywords

Effective preparation of a monoclonal antibody against human chromogranin A for immunohistochemical diagnosis

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recommendations! Published in 2018 at "BMC Biotechnology"

DOI: 10.1186/s12896-018-0436-z

Abstract: BackgroundHuman chromogranin A (CgA) is a ~ 49 kDa secreted protein mainly from neuroendocrine cells and endocrine cells. The CgA values in the diagnosis of tumor, and in the potential role in prognostic and predictive tumor as… read more here.

Keywords: protein; diagnosis; chromogranin; cga ... See more keywords

MON-098 Ovaries, Hormones And Tumors: Navigating This Complexity, A Case Report

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recommendations! Published in 2024 at "Journal of the Endocrine Society"

DOI: 10.1210/jendso/bvae163.2411

Abstract: Abstract M.D. Chandra: None. Introduction: Neuroendocrine tumors (NETs) are rare tumors usually originating in the GI tract and lung. An ovarian neuroendocrine tumor is a rare entity, accounting for 0.5% of all carcinoid tumors and… read more here.

Keywords: well differentiated; chromogranin; tract; tumor ... See more keywords

Chromogranin A plasma levels predict mortality in COVID-19

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recommendations! Published in 2022 at "PLoS ONE"

DOI: 10.1371/journal.pone.0267235

Abstract: Background Chromogranin A (CgA) and its fragment vasostatin I (VS-I) are secreted in the blood by endocrine/neuroendocrine cells and regulate stress responses. Their involvement in Coronavirus 2019 disease (COVID-19) has not been investigated. Methods CgA… read more here.

Keywords: cga levels; mortality; iqr; covid ... See more keywords