Chromothripsis and Chromoplexy Are Associated with DNA Instability and Adverse Clinical Outcome in Multiple Myeloma
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DOI: 10.1182/blood-2018-99-117359
Abstract: Introduction: Chromothripsis and chromoplexy are gross structural events that deregulate multiple genes simultaneously and may help explain rapid changes in clinical behavior. Previous screening studies in multiple myeloma (MM) using copy number arrays have identified… read more here.
Keywords: consultancy honoraria; corporation employment; chromothripsis; celgene corporation ... See more keywords