Combing Chromosomal DNA Mediated by the SMC Complex: Structure and Mechanisms
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DOI: 10.1002/bies.201700166
Abstract: Genome maintenance requires various nucleoidâassociated factors in prokaryotes. Among them, the SMC (Structural Maintenance of Chromosomes) protein has been thought to play a static role in the organization and segregation of the chromosome during cell… read more here.
Keywords: dna mediated; dna; mediated smc; smc complex ... See more keywords
Exclusive use of digital PCR allows an absolute assay of heat-killed Lactobacilli in foods targeting multiple copies of 16S rDNA
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DOI: 10.1038/s41598-020-69206-5
Abstract: The real-time PCR (qPCR) and digital PCR (dPCR) to amplify a single-copy of house-keeping genes (i.e., hsp60, pheS or tuf) are used for the assay of limited microbial species. In general, with a single-copy gene,… read more here.
Keywords: 16s rdna; heat killed; copies 16s; rdna ... See more keywords
Physical modeling of the spreading of epigenetic modifications through transient DNA looping
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Physics A: Mathematical and Theoretical"
DOI: 10.1088/1751-8121/ab41d2
Abstract: We utilize theoretical modeling to explore the physical mechanisms that govern the spreading of epigenetic modifications along chromosomal DNA. We focus on a particular modification, methylation of lysine 9 of histone H3 (H3K9), which is… read more here.
Keywords: epigenetic modifications; dna; physical modeling; spreading epigenetic ... See more keywords
Self-cytoplasmic DNA upregulates the mutator enzyme APOBEC3A leading to chromosomal DNA damage
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DOI: 10.1093/nar/gkx001
Abstract: Abstract Foreign and self-cytoplasmic DNA are recognized by numerous DNA sensor molecules leading to the production of type I interferons. Such DNA agonists should be degraded otherwise cells would be chronically stressed. Most human APOBEC3… read more here.
Keywords: dna damage; apobec3a; dna; self cytoplasmic ... See more keywords
Trends in Reported Sexual Behavior and Y-Chromosomal DNA Detection Among Female Sex Workers in the Senegal Preexposure Prophylaxis Demonstration Project
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DOI: 10.1097/olq.0000000000001175
Abstract: A study among female sex workers in Senegal found no evidence of increased sexual risk behavior after preexposure prophylaxis initiation as measured by self-report or Y-chromosomal DNA detection. Supplemental digital content is available in the… read more here.
Keywords: dna detection; self reported; chromosomal dna; sex ... See more keywords
Securing IP Cores for DSP Applications Using Structural Obfuscation and Chromosomal DNA Impression
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DOI: 10.1109/access.2022.3174349
Abstract: This paper presents a novel hybrid methodology with structural obfuscation and encrypted chromosomal DNA impression to secure intellectual property (IP) cores of digital signal processing (DSP) applications. The proposed work offers security against altering register… read more here.
Keywords: dna impression; chromosomal dna; obfuscation; structural obfuscation ... See more keywords
Organization of Chromosomal DNA by SMC Complexes.
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DOI: 10.1146/annurev-genet-112618-043633
Abstract: Structural maintenance of chromosomes (SMC) complexes are key organizers of chromosome architecture in all kingdoms of life. Despite seemingly divergent functions, such as chromosome segregation, chromosome maintenance, sister chromatid cohesion, and mitotic chromosome compaction, it… read more here.
Keywords: dna; genetics; dna smc; organization chromosomal ... See more keywords
Classification of Chromosomal DNA Sequences Using Hybrid Deep Learning Architectures
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DOI: 10.2174/1574893615666200224095531
Abstract: Chromosomal DNA contains most of the genetic information of eukaryotes and plays an important role in the growth, development and reproduction of living organisms. Most chromosomal DNA sequences are known to wrap around histones, and… read more here.
Keywords: classification; dna sequences; dna; deep learning ... See more keywords
Factors Impacting Invader-Mediated Recognition of Double-Stranded DNA
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DOI: 10.3390/molecules28010127
Abstract: The development of chemically modified oligonucleotides enabling robust, sequence-unrestricted recognition of complementary chromosomal DNA regions has been an aspirational goal for scientists for many decades. While several groove-binding or strand-invading probes have been developed towards… read more here.
Keywords: recognition; chromosomal dna; dna; dna targets ... See more keywords