Graphene oxide regulates cox2 in human embryonic kidney 293T cells via epigenetic mechanisms: dynamic chromosomal interactions
Sign Up to like & getrecommendations! Published in 2018 at "Nanotoxicology"
DOI: 10.1080/17435390.2018.1425498
Abstract: Abstract To extend the applications of engineered nanomaterials, such as graphene oxide (GO), it is necessary to minimize cytotoxicity. However, the mechanisms underlying this cytotoxicity are unclear. Dynamic chromosomal interactions have been used to illustrate… read more here.
Keywords: graphene oxide; chromosomal interactions; embryonic kidney; dynamic chromosomal ... See more keywords
Chicdiff: a computational pipeline for detecting differential chromosomal interactions in Capture Hi-C data
Sign Up to like & getrecommendations! Published in 2019 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btz450
Abstract: Abstract Summary Capture Hi-C is a powerful approach for detecting chromosomal interactions involving, at least on one end, DNA regions of interest, such as gene promoters. We present Chicdiff, an R package for robust detection… read more here.
Keywords: capture data; chromosomal interactions; data chicdiff; interactions capture ... See more keywords
Probabilistic establishment of speckle-associated inter-chromosomal interactions.
Sign Up to like & getrecommendations! Published in 2023 at "Nucleic acids research"
DOI: 10.1093/nar/gkad211
Abstract: Inter-chromosomal interactions play a crucial role in genome organization, yet the organizational principles remain elusive. Here, we introduce a novel computational method to systematically characterize inter-chromosomal interactions using in situ Hi-C results from various cell… read more here.
Keywords: inter; speckle associated; associated inter; chromosomal interactions ... See more keywords
Cis- and Trans-chromosomal Interactions Define Pericentric Boundaries in the Absence of Conventional Heterochromatin
Sign Up to like & getrecommendations! Published in 2019 at "Genetics"
DOI: 10.1534/genetics.119.302179
Abstract: The molecular cues for CENPA positioning in epigenetically regulated centromeres is elusive. Candida albicans has small regional non-repetitive centromeres that do not harbor conventional heterochromatin. Deletion of native centromere leads to activation of a neocentromere...… read more here.
Keywords: chromosomal interactions; conventional heterochromatin; cen; trans chromosomal ... See more keywords