Use of a plasma focus device to study pulsed x-ray effects on peripheral blood lymphocytes: Analysis of chromosome aberrations
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Applied Physics"
DOI: 10.1063/5.0141529
Abstract: X-ray pulses (full width at half maximum ∼ 90 ns, dose rate ∼ 107 Gy s−1) were used to irradiate the monolayer of peripheral blood mononucleated cells using the PF-2kJ kilojoule plasma focus device. Four different exposure conditions were evaluated… read more here.
Keywords: plasma focus; chromosome aberrations; peripheral blood; focus device ... See more keywords
The effects of DNA repair polymorphisms on chromosome aberrations in the population of Kazakhstan
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Radiation Biology"
DOI: 10.1080/09553002.2020.1711460
Abstract: Abstract Purpose: To analyze the effects of DNA repair polymorphism and other factors on the frequency chromosome aberrations in an irradiated cohort of subjects living around the Semipalatinsk nuclear test site and non-exposed group of… read more here.
Keywords: frequency chromosome; dna repair; effects dna; chromosome aberrations ... See more keywords
Frequencies of Chromosome Aberrations are Lower in Splenic Lymphocytes from Mice Continuously Exposed to Very Low-Dose-Rate Gamma Rays Compared with Non-Irradiated Control Mice.
Sign Up to like & getrecommendations! Published in 2022 at "Radiation research"
DOI: 10.1667/rade-21-00159
Abstract: Chromosome aberrations have been one of the most sensitive and reliable biomarkers of exposure to ionizing radiation. Using the multiplex fluorescence in situ hybridization (M-FISH) technique, we compared the changes, over time, in the frequencies… read more here.
Keywords: chromosome aberrations; non irradiated; mice continuously; dose ... See more keywords
Dose-Dependent Transmissibility of Chromosome Aberrations in Human Lymphocytes at First Mitosis. II. Biological Effectiveness of Heavy Charged Particles Versus Gamma Rays
Sign Up to like & getrecommendations! Published in 2023 at "Radiation Research"
DOI: 10.1667/rade-22-00141.1
Abstract: Chromosome aberrations (CAs) are large scale structural rearrangements to the genome that have been used as a proxy endpoint of mutagenic and carcinogenic potential. And yet, many types of CAs are incapable of causing either… read more here.
Keywords: chromosome aberrations; biological effectiveness; gamma; human lymphocytes ... See more keywords
Both Epimutations and Chromosome Aberrations Affect Multiple Imprinted Loci in Aggressive Wilms Tumors
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DOI: 10.3390/cancers12113411
Abstract: Simple Summary About 7% of all children’s malignancies are represented by the embryonal renal cancer Wilms tumor (WT). Since methylation imprinting alterations at multiple loci dictated by chromosome copy-number variations have been recently demonstrated in… read more here.
Keywords: chromosome aberrations; multiple imprinted; methylation; imprinted loci ... See more keywords
Nonclonal Chromosome Aberrations and Genome Chaos in Somatic and Germ Cells from Patients and Survivors of Hodgkin Lymphoma
Sign Up to like & getrecommendations! Published in 2019 at "Genes"
DOI: 10.3390/genes10010037
Abstract: Anticancer regimens for Hodgkin lymphoma (HL) patients include highly genotoxic drugs that have been very successful in killing tumor cells and providing a 90% disease-free survival at five years. However, some of these treatments do… read more here.
Keywords: hodgkin lymphoma; nonclonal chromosome; chromosomal aberrations; cells patients ... See more keywords
Impact of Radiation Quality on Microdosimetry and Chromosome Aberrations for High-Energy (>250 MeV/n) Ions
Sign Up to like & getrecommendations! Published in 2022 at "Life"
DOI: 10.3390/life12030358
Abstract: Studying energy deposition by space radiation at the cellular scale provides insights on health risks to astronauts. Using the Monte Carlo track structure code RITRACKS, and the chromosome aberrations code RITCARD, we performed a modeling… read more here.
Keywords: chromosome aberrations; high energy; beam; energy ... See more keywords
The Relationship between Screening Markers in the First Trimester of Pregnancy and Chromosome Aberrations
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DOI: 10.4103/ijpvm.ijpvm_572_20
Abstract: Background: This study was designed and performed to investigate the relationship between fetal chromosome aberrations and screening markers in the first trimester of pregnancy in order to prevent the birth of infants with chromosome aberrations… read more here.
Keywords: chromosome aberrations; screening markers; relationship; first trimester ... See more keywords