The prognostic significance of chromosome 17 abnormalities in patients with myelodysplastic syndrome treated with 5‐azacytidine: Results from the Hellenic 5‐azacytidine registry
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Medicine"
DOI: 10.1002/cam4.2090
Abstract: In patients with myelodysplastic syndrome (MDS), the prognostic significance of chromosome 17 abnormalities has not yet been fully elucidated, except for isochromosome 17q that has been characterized as an intermediate risk abnormality in the Revised… read more here.
Keywords: chromosome abnormalities; significance chromosome; abnormality; chromosome ... See more keywords
Current controversies in prenatal diagnosis 2: Cell‐free DNA prenatal screening should be used to identify all chromosome abnormalities
Sign Up to like & getrecommendations! Published in 2018 at "Prenatal Diagnosis"
DOI: 10.1002/pd.5216
Abstract: Noninvasive prenatal testing (NIPT) using cell‐free DNA (cfDNA) from maternal serum has been clinically available since 2011. This technology has revolutionized our ability to screen for the common aneuploidies trisomy 21 (Down syndrome), trisomy 18,… read more here.
Keywords: prenatal screening; chromosome abnormalities; free dna; cell free ... See more keywords
Acute myeloid leukemia or myelodysplastic syndrome with chromosome 17 abnormalities and long-term outcomes with or without hematopoietic stem cell transplantation.
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DOI: 10.1016/j.leukres.2020.106402
Abstract: INTRODUCTION Chromosome 17 abnormalities, especially disorders of the 17p region and including TP53 gene mutations, result in very low rates of cure for patients with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) treated with… read more here.
Keywords: aml mds; chromosome abnormalities; myeloid leukemia; hct ... See more keywords
The Relationship between Human Embryo Parameters and De Novo Chromosomal Abnormalities in Preimplantation Genetic Testing Cycles
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DOI: 10.1155/2022/9707081
Abstract: Design In total, 456 PGT cycles, including 283 PGT-SR cycles and 173 PGT-A cycles, were assessed through comprehensive chromosome screening (CCS) from January 2017 to June 2020 at the Department of Reproductive Medicine of the… read more here.
Keywords: chromosome abnormalities; chromosome; pgt cycles; novo chromosome ... See more keywords
Chromosome 1 abnormalities and clinical outcomes in multiple myeloma in the era of novel agents.
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DOI: 10.1200/jco.2019.37.15_suppl.8044
Abstract: 8044 Background: Abnormalities of chromosome 1 (C1A) are common genetic mutations in patients (pts) with Multiple Myeloma (MM). While several small studies have reported worse outcomes for C1A, the prevalence, real-world treatment and outcomes for… read more here.
Keywords: chromosome abnormalities; pts c1a; multiple myeloma; abnormalities clinical ... See more keywords
Prenatal diagnosis of non-mosaic sex chromosome abnormalities: a 10-year experience from a tertiary referral center
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DOI: 10.1515/jpm-2022-0552
Abstract: Abstract Objectives The aim of this study was to explore the frequency and profile of non-mosaic sex chromosome abnormalities detected in prenatal diagnosis over the past 10 years. Methods We retrospectively reviewed pregnancies diagnosed with… read more here.
Keywords: sex chromosome; non mosaic; sex; chromosome abnormalities ... See more keywords
Sex chromosome abnormalities and psychiatric diseases
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DOI: 10.18632/oncotarget.13962
Abstract: Excesses of sex chromosome abnormalities in patients with psychiatric diseases have recently been observed. It remains unclear whether sex chromosome abnormalities are related to sex differences in some psychiatric diseases. While studies showed evidence of… read more here.
Keywords: psychiatric diseases; chromosome abnormalities; sex chromosome; abnormalities psychiatric ... See more keywords
Cell-Free DNA Screening for Sex Chromosome Abnormalities and Pregnancy Outcomes, 2018–2020: A Retrospective Analysis
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DOI: 10.3390/jpm12010048
Abstract: To evaluate the efficacy of non-invasive prenatal screening (NIPT) for detecting fetal sex chromosome abnormalities, a total of 639 women carrying sex chromosome abnormalities were selected from 222,107 pregnant women who participated in free NIPT… read more here.
Keywords: sex chromosome; chromosome; pregnancy outcomes; chromosome abnormalities ... See more keywords
Detection of chromosome abnormalities using current noninvasive prenatal testing: A multi-center comparative study.
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DOI: 10.5582/bst.2018.01044
Abstract: Noninvasive prenatal testing (NIPT) is increasingly recognized and utilized in the antenatal care field. In the current study, we aimed to evaluate the clinical application and compare test outcomes of two generations of currently used… read more here.
Keywords: chromosome abnormalities; prenatal testing; group; study ... See more keywords