MCPH1, mutated in primary microcephaly, is required for efficient chromosome alignment during mitosis
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-12793-7
Abstract: MCPH1 gene, mutated in primary microcephaly, regulates cell progression into mitosis. While this role has been extensively investigated in the context of DNA damage, its function during unperturbed cell cycles has been given less attention.… read more here.
Keywords: primary microcephaly; mitosis; required efficient; chromosome alignment ... See more keywords
Bisphenol B Exposure Disrupts Mouse Oocyte Meiotic Maturation in vitro Through Affecting Spindle Assembly and Chromosome Alignment
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2020.616771
Abstract: Bisphenol B (BPB), a substitute of bisphenol A (BPA), is widely used in the polycarbonate plastic and resins production. However, BPB proved to be not a safe alternative to BPA, and as an endocrine disruptor,… read more here.
Keywords: spindle assembly; chromosome alignment; spindle; meiotic maturation ... See more keywords