ZYP1-mediated recruitment of PCH2 to the synaptonemal complex remodels the chromosome axis leading to crossover restriction
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DOI: 10.1093/nar/gkac1160
Abstract: Abstract Chromosome axis-associated HORMA domain proteins (HORMADs), e.g. ASY1 in Arabidopsis, are crucial for meiotic recombination. ASY1, as other HORMADs, is assembled on the axis at early meiosis and depleted when homologous chromosomes synapse. Puzzlingly,… read more here.
Keywords: mediated recruitment; crossover; zyp1 mediated; pch2 ... See more keywords
Trim41 is required to regulate chromosome axis protein dynamics and meiosis in male mice
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DOI: 10.1371/journal.pgen.1010241
Abstract: Meiosis is a hallmark event in germ cell development that accompanies sequential events executed by numerous molecules. Therefore, characterization of these factors is one of the best strategies to clarify the mechanism of meiosis. Here,… read more here.
Keywords: chromosome axis; chromosome; protein; trim41 required ... See more keywords
Differentiated function and localisation of SPO11-1 and PRD3 on the chromosome axis during meiotic DSB formation in Arabidopsis thaliana
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DOI: 10.1371/journal.pgen.1010298
Abstract: During meiosis, DNA double-strand breaks (DSBs) occur throughout the genome, a subset of which are repaired to form reciprocal crossovers between chromosomes. Crossovers are essential to ensure balanced chromosome segregation and to create new combinations… read more here.
Keywords: spo11 prd3; chromosome axis; spo11; localisation ... See more keywords