DNA methylome combined with chromosome cluster-oriented analysis provides an early signature for cutaneous melanoma aggressiveness
Sign Up to like & getrecommendations! Published in 2022 at "eLife"
DOI: 10.1101/2022.04.11.487909
Abstract: Aberrant DNA methylation is a well-known feature of tumours and has been associated with metastatic melanoma. However, since melanoma cells are highly heterogeneous, it has been challenging to use affected genes to predict tumour aggressiveness,… read more here.
Keywords: cell; melanoma; cluster oriented; dna methylome ... See more keywords
SupCAM: Chromosome cluster types identification using supervised contrastive learning with category-variant augmentation and self-margin loss
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2023.1109269
Abstract: Chromosome segmentation is a crucial analyzing task in karyotyping, a technique used in experiments to discover chromosomal abnormalities. Chromosomes often touch and occlude with each other in images, forming various chromosome clusters. The majority of… read more here.
Keywords: identification; loss; chromosome; chromosome segmentation ... See more keywords