Mitotic chromosome organization: General rules meet species-specific variability
Sign Up to like & getrecommendations! Published in 2020 at "Computational and Structural Biotechnology Journal"
DOI: 10.1016/j.csbj.2020.01.006
Abstract: Research on the formation of mitotic chromosomes from interphase chromatin domains, ongoing for several decades, made significant progress in recent years. It was stimulated by the development of advanced microscopic techniques and implementation of chromatin… read more here.
Keywords: chromosome organization; mitotic chromosomes; organization general; mitotic chromosome ... See more keywords
The ubiquitin-proteasome system regulates meiotic chromosome organization.
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2106902119
Abstract: SignificanceMeiotic crossover recombination is required for faithful chromosome segregation and promotes genetic diversity by reshuffling alleles between parental chromosomes. Meiotic chromosomes are organized into arrays of loops that are anchored to the proteinaceous axes. The… read more here.
Keywords: proteasome system; chromosome organization; chromosome; meiotic chromosome ... See more keywords
Effects of human sex chromosome dosage on spatial chromosome organization
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Biology of the Cell"
DOI: 10.1091/mbc.e18-06-0359
Abstract: Sex chromosome aneuploidies (SCAs) are common genetic syndromes characterized by the presence of an aberrant number of X and Y chromosomes due to meiotic defects. These conditions impact the structure and function of diverse tissues,… read more here.
Keywords: chromosome organization; sex chromosome; effects human; chromosome ... See more keywords
Meiotic chromosome organization and crossover patterns
Sign Up to like & getrecommendations! Published in 2022 at "Biology of Reproduction"
DOI: 10.1093/biolre/ioac040
Abstract: Abstract Meiosis is the foundation of sexual reproduction, and crossover recombination is one hallmark of meiosis. Crossovers establish the physical connections between homolog chromosomes (homologs) for their proper segregation and exchange DNA between homologs to… read more here.
Keywords: meiotic chromosome; crossover; chromosome organization; crossover patterns ... See more keywords
Non-Rabl chromosome organization in endoreduplicated nuclei of barley embryo and endosperm tissues.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of experimental botany"
DOI: 10.1093/jxb/erad036
Abstract: Rabl organization is a type of interphase chromosome arrangement with centromeres and telomeres clustering at opposite nuclear poles. Here, we analyzed nuclear morphology and chromosome organization in cycling and endoreduplicated nuclei isolated from embryo and… read more here.
Keywords: endosperm tissues; endoreduplicated nuclei; chromosome organization; organization ... See more keywords
A low Smc flux avoids collisions and facilitates chromosome organization in Bacillus subtilis
Sign Up to like & getrecommendations! Published in 2021 at "eLife"
DOI: 10.7554/elife.65467
Abstract: SMC complexes are widely conserved ATP-powered DNA-loop-extrusion motors indispensable for organizing and faithfully segregating chromosomes. How SMC complexes translocate along DNA for loop extrusion and what happens when two complexes meet on the same DNA… read more here.
Keywords: chromosome organization; smc; smc complexes; smc flux ... See more keywords