Recent Advances in Helicobacter pylori Replication: Possible Implications in Adaptation to a Pathogenic Lifestyle and Perspectives for Drug Design.
Sign Up to like & getrecommendations! Published in 2017 at "Current topics in microbiology and immunology"
DOI: 10.1007/978-3-319-50520-6_4
Abstract: DNA replication is an important step in the life cycle of every cell that ensures the continuous flow of genetic information from one generation to the next. In all organisms, chromosome replication must be coordinated… read more here.
Keywords: chromosome replication; pylori chromosome; drug; helicobacter pylori ... See more keywords
Division stochasticity can be transmitted to protein expression through chromosome replication
Sign Up to like & getrecommendations! Published in 2020 at "IFAC-PapersOnLine"
DOI: 10.1016/j.ifacol.2020.12.1170
Abstract: Abstract Stochastic fluctuations (noise) are a fundamental characteristic of protein production. In this work, we explore how these fluctuations can originate from the stochasticity on division events. Here we consider the classical gene expression model… read more here.
Keywords: expression; chromosome replication; division; stochasticity ... See more keywords
Multiple roles of Pol epsilon in eukaryotic chromosome replication
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DOI: 10.1042/bst20210082
Abstract: Pol epsilon is a tetrameric assembly that plays distinct roles during eukaryotic chromosome replication. It catalyses leading strand DNA synthesis; yet this function is dispensable for viability. Its non-catalytic domains instead play an essential role… read more here.
Keywords: multiple roles; chromosome replication; eukaryotic chromosome; pol epsilon ... See more keywords
The Caulobacter crescentus DciA promotes chromosome replication through topological loading of the DnaB replicative helicase at replication forks
Sign Up to like & getrecommendations! Published in 2022 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkac1146
Abstract: Abstract The replicative DNA helicase translocates on single-stranded DNA to drive replication forks during chromosome replication. In most bacteria the ubiquitous replicative helicase, DnaB, co-evolved with the accessory subunit DciA, but how they function remains… read more here.
Keywords: dcia; dnab; replication; helicase ... See more keywords