Enzymatic Supercoiling of Bacterial Chromosomes Facilitates Genome Manipulation
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DOI: 10.1021/acssynbio.2c00353
Abstract: The physical stability of bacterial chromosomes is important for their in vitro manipulation, while genetic stability is important in vivo. However, extracted naked chromosomes in the open circular form are fragile due to nicks and… read more here.
Keywords: bacterial chromosomes; enzymatic supercoiling; chromosomes facilitates; supercoiling bacterial ... See more keywords