APOBEC3-dependent kataegis and TREX1-driven chromothripsis during telomere crisis
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DOI: 10.1038/s41588-020-0667-5
Abstract: Chromothripsis and kataegis are frequently observed in cancer and may arise from telomere crisis, a period of genome instability during tumorigenesis when depletion of the telomere reserve generates unstable dicentric chromosomes 1 – 5 .… read more here.
Keywords: chromothripsis; chromothripsis kataegis; trex1; telomere crisis ... See more keywords