Chronic Allergen Challenge Induces Corticosteroid Insensitivity With Persistent Airway Remodeling and Type 2 Inflammation
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DOI: 10.3389/fphar.2022.855247
Abstract: Type 2-high severe asthma is described as a distinct endotype with Th2 inflammation, high eosinophil lung infiltration, impaired lung function, and reduced corticosteroid sensitivity. While the inflammatory milieu is similar to mild asthma, patients with… read more here.
Keywords: inflammation; type inflammation; asthma; chronic allergen ... See more keywords