Chronic cocaine causes age-dependent increases in risky choice in both males and females.
Sign Up to like & getrecommendations! Published in 2022 at "Behavioral neuroscience"
DOI: 10.1037/bne0000509
Abstract: Individuals who use cocaine exhibit maladaptive decision-making, overweighting rewards, and underweighting potential risks. We previously showed that chronic cocaine self-administration in young adult male rats causes long-lasting increases in risk taking. The present study expanded… read more here.
Keywords: cocaine self; administration; risk taking; chronic cocaine ... See more keywords
Effects of chronic cocaine and ethanol self‐administration on brain dopamine receptors in a rhesus monkey model of polysubstance abuse
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DOI: 10.1111/adb.13219
Abstract: Most individuals with cocaine use disorder also use alcohol; however, little is known about the behavioural and pharmacological mechanisms that promote co‐abuse. For example, although studies in humans and animals have documented that chronic use… read more here.
Keywords: cocaine self; self administration; chronic cocaine; effects chronic ... See more keywords
Chronic cocaine induces HIF-VEGF pathway activation along with angiogenesis in the brain
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DOI: 10.1371/journal.pone.0175499
Abstract: Cocaine induces vasoconstriction in cerebral vessels, which with repeated use can result in transient ischemic attacks and cerebral strokes. However, the neuroadaptations that follow cocaine’s vasoconstricting effects are not well understood. Here, we investigated the… read more here.
Keywords: hif vegf; microvascular density; cocaine induces; brain ... See more keywords
Psychomotor Symptoms in Chronic Cocaine Users: An Interpretative Model
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DOI: 10.3390/ijerph19031897
Abstract: According to the latest estimates, there are around 24.6 million cocaine users worldwide, and it is estimated that around a quarter of the population worldwide has used cocaine at some point in their lifetime. It… read more here.
Keywords: psychomotor symptoms; chronic cocaine; symptoms chronic; cocaine ... See more keywords