Hyperactive neuronal autophagy depletes BDNF and impairs adult hippocampal neurogenesis in a corticosterone-induced mouse model of depression
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DOI: 10.7150/thno.81067
Abstract: Background: Depression is a mental disorder that poses a serious threat to human health. Adult hippocampal neurogenesis (AHN) is closely associated with the efficacy of antidepressants. Chronic treatment with corticosterone (CORT), a well-validated pharmacological stressor,… read more here.
Keywords: chronic cort; depression; neuronal autophagy; hippocampal neurogenesis ... See more keywords