Prediction of Biochemical Nonresolution in Patients with Chronic Drug-induced Liver Injury: A Large Multicenter Study.
Sign Up to like & getrecommendations! Published in 2021 at "Hepatology"
DOI: 10.1002/hep.32283
Abstract: BACKGROUND AND AIMS To clarify high-risk factors and develop a novel nomogram model to predict biochemical resolution (BR) or not (BNR) in patients with chronic drug-induced liver injury (DILI). APPROACH AND RESULTS Retrospectively, 3,655 out… read more here.
Keywords: chronic drug; biochemical nonresolution; liver injury; patients chronic ... See more keywords
Analysis of Immunometabolic Profiles in Patients With Chronic Drug‐Induced Liver Injury and Validation in Mice to Reveal Potential Mechanisms
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Gastroenterology and Hepatology"
DOI: 10.1111/jgh.16876
Abstract: The mechanism underlying chronic drug‐induced liver injury (DILI) remains unclear. Immune activation is a common feature of DILI progression and is closely associated with metabolism. We explored the immunometabolic profile of chronic DILI and the… read more here.
Keywords: liver injury; induced liver; chronic drug; drug induced ... See more keywords
Serum Metabolomic Analysis of Chronic Drug-Induced Liver Injury With or Without Cirrhosis
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DOI: 10.3389/fmed.2021.640799
Abstract: Background: Chronic drug-induced liver injury (DILI) occurs in up to 20% of all DILI patients. It presents a chronic pattern with persistent or relapsed episodes and may even progress to cirrhosis. However, its underlying development… read more here.
Keywords: chronic drug; chronic dili; cirrhosis; drug induced ... See more keywords
3D Printed Cell Culture Chamber for Testing the Effect of Pump-Based Chronic Drug Delivery on Inner Ear Tissue
Sign Up to like & getrecommendations! Published in 2022 at "Biomolecules"
DOI: 10.3390/biom12040589
Abstract: Cochlear hair cell damage and spiral ganglion neuron (SGN) degeneration are the main causes of sensory neural hearing loss. Cochlear implants (CIs) can replace the function of the hair cells and stimulate the SGNs electrically.… read more here.
Keywords: inner ear; chronic drug; pump; drug delivery ... See more keywords