A tool for monitoring cell type–specific focused ultrasound neuromodulation and control of chronic epilepsy
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2206828119
Abstract: Significance Ultrasound can be focused through skull onto the deep brain, altering neural activity noninvasively. Despite its broad utility, the action of focused ultrasound on specific cell types is almost entirely unknown. Understanding cell type–specific… read more here.
Keywords: cell; chronic epilepsy; focused ultrasound; type specific ... See more keywords
Seizures and risk of epilepsy in autoimmune and other inflammatory encephalitis
Sign Up to like & getrecommendations! Published in 2017 at "Current Opinion in Neurology"
DOI: 10.1097/wco.0000000000000449
Abstract: Purpose of review The aim of this study was to assess the seizure manifestations and risk of epilepsy in encephalitis associated with antibodies against neuronal cell-surface (autoimmune encephalitis) or myelin-associated antigens, and to review several… read more here.
Keywords: autoimmune encephalitis; rasmussen encephalitis; encephalitis; risk epilepsy ... See more keywords
Neurofilament light chain - a possible fluid biomarker in the intrahippocampal kainic acid mouse model for chronic epilepsy?
Sign Up to like & getrecommendations! Published in 2023 at "Epilepsia"
DOI: 10.1111/epi.17669
Abstract: OBJECTIVE In the management of epilepsy, there is an ongoing quest to discover new biomarkers to improve the diagnostic process, the monitoring of disease progression, and the evaluation of treatment responsiveness. In this regard, biochemical… read more here.
Keywords: chronic epilepsy; kainic acid; fluid biomarker; nfl levels ... See more keywords
MicroRNA expression profiles in chronic epilepsy rats and neuroprotection from seizures by targeting miR-344a
Sign Up to like & getrecommendations! Published in 2017 at "Neuropsychiatric Disease and Treatment"
DOI: 10.2147/ndt.s141062
Abstract: MicroRNA (miRNA) is believed to play a crucial role in the cause and treatment of epilepsy by controlling gene expression. However, it is still unclear how miRNA profiles change after multiple prolonged seizures and aggravation… read more here.
Keywords: epilepsy; mir 344a; treatment; expression ... See more keywords
Sp1-Mediated Prdx6 Upregulation Leads to Clasmatodendrosis by Increasing Its aiPLA2 Activity in the CA1 Astrocytes in Chronic Epilepsy Rats
Sign Up to like & getrecommendations! Published in 2022 at "Antioxidants"
DOI: 10.3390/antiox11101883
Abstract: Clasmatodendrosis is an autophagic astroglial degeneration (a non-apoptotic (type II) programmed cell death) whose underlying mechanisms are fully understood. Peroxiredoxin-6 (Prdx6), the “non-selenium glutathione peroxidase (NSGPx)”, is the only member of the 1-cysteine peroxiredoxin family.… read more here.
Keywords: chronic epilepsy; clasmatodendrosis; aipla2 activity; epilepsy rats ... See more keywords
Deregulation of Astroglial TASK-1 K+ Channel Decreases the Responsiveness to Perampanel-Induced AMPA Receptor Inhibition in Chronic Epilepsy Rats
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24065491
Abstract: Tandem of P domains in a weak inwardly rectifying K+ channel (TWIK)-related acid sensitive K+-1 channel (TASK-1) is activated under extracellular alkaline conditions (pH 7.2–8.2), which are upregulated in astrocytes (particularly in the CA1 region)… read more here.
Keywords: chronic epilepsy; deregulation astroglial; task; epilepsy rats ... See more keywords