Chronic Fluoxetine Induces Activity Changes in Recovery From Poststroke Anxiety, Depression, and Cognitive Impairment
Sign Up to like & getrecommendations! Published in 2017 at "Neurotherapeutics"
DOI: 10.1007/s13311-017-0590-3
Abstract: Poststroke depression (PSD) is a common outcome of stroke that limits recovery and is only partially responsive to chronic antidepressant treatment. In order to elucidate changes in the cortical-limbic circuitry associated with PSD and its… read more here.
Keywords: recovery; depression; chronic fluoxetine; anxiety depression ... See more keywords
Sex-dependent effects of chronic fluoxetine exposure during adolescence on passive avoidance memory, nociception, and prefrontal brain-derived neurotrophic factor mRNA expression
Sign Up to like & getrecommendations! Published in 2020 at "Brain Research Bulletin"
DOI: 10.1016/j.brainresbull.2020.06.009
Abstract: Fluoxetine, a common antidepressant drug, is widely used for mental disorders therapy in adolescents. Previous animal experiments have indicated that exposure to fluoxetine during adolescence leads to persistent behavioral changes and neuroplasticity in the hippocampal… read more here.
Keywords: passive avoidance; chronic fluoxetine; fluoxetine; mrna expression ... See more keywords
Chronic fluoxetine treatment impairs motivation and reward learning by affecting neuronal plasticity in the central amygdala
Sign Up to like & getrecommendations! Published in 2020 at "British Journal of Pharmacology"
DOI: 10.1111/bph.15319
Abstract: The therapeutic effects of fluoxetine are believed to be due to increasing neuronal plasticity and reversing some learning deficits. Nevertheless, a growing amount of evidence shows adverse effects of this drug on cognition and some… read more here.
Keywords: plasticity; chronic fluoxetine; neuronal plasticity; impairs motivation ... See more keywords