Chronic hyperglycemia impairs hippocampal neurogenesis and memory in an Alzheimer’s disease mouse model
Sign Up to like & getrecommendations! Published in 2020 at "Neurobiology of Aging"
DOI: 10.1016/j.neurobiolaging.2020.04.003
Abstract: During aging, lifestyle-related factors shape the brain's response to insults and modulate the progression of neurodegenerative pathologies such as Alzheimer's disease (AD). This is the case for chronic hyperglycemia associated with type 2 diabetes, which… read more here.
Keywords: hyperglycemia impairs; alzheimer disease; chronic hyperglycemia; hyperglycemia ... See more keywords
Chronic hyperglycemia is related to poor functional outcome after acute ischemic stroke
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DOI: 10.1177/1747493016676619
Abstract: Background Acute hyperglycemia is associated with poor functional outcome after ischemic stroke, but the association between chronic antecedent hyperglycemia and outcome is unclear. Aim We assessed the association between chronic hyperglycemia, measured by hemoglobin A1c,… read more here.
Keywords: ischemic stroke; chronic hyperglycemia; hyperglycemia; functional outcome ... See more keywords
Circulating pentraxin 3 is positively associated with chronic hyperglycemia but negatively associated with plasma aldosterone concentration
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DOI: 10.1371/journal.pone.0196526
Abstract: Pentraxin 3 (PTX3) is reported to be a vascular inflammation marker providing prognostic information of vasculopathy. Until today, however, the effect of aldosterone or oxidative stress on the regulation of PTX3 is unknown. In present… read more here.
Keywords: aldosterone; chronic hyperglycemia; ptx3; plasma aldosterone ... See more keywords
Chronic Hyperglycemia Drives Functional Impairment of Lymphocytes in Diabetic INSC94Y Transgenic Pigs
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DOI: 10.3389/fimmu.2020.607473
Abstract: People with diabetes mellitus have an increased risk for infections, however, there is still a critical gap in precise knowledge about altered immune mechanisms in this disease. Since diabetic INSC94Y transgenic pigs exhibit elevated blood… read more here.
Keywords: insc94y transgenic; chronic hyperglycemia; diabetic insc94y; transgenic pigs ... See more keywords