CT findings associated with survival in chronic hypersensitivity pneumonitis
Sign Up to like & getrecommendations! Published in 2017 at "European Radiology"
DOI: 10.1007/s00330-017-4936-3
Abstract: AbstractObjectivesTo identify CT findings in chronic hypersensitivity pneumonitis (cHP) associated with survival.Material and methodsTwo thoracic radiologists assessed CT scans for specific imaging findings and patterns in 132 subjects with cHP. Survival analyses were performed.ResultsThe majority… read more here.
Keywords: fibrosis; associated survival; chronic hypersensitivity; hypersensitivity pneumonitis ... See more keywords
Quantitative CT Analysis in Chronic Hypersensitivity Pneumonitis: A Convolutional Neural Network Approach.
Sign Up to like & getrecommendations! Published in 2020 at "Academic radiology"
DOI: 10.1016/j.acra.2020.10.009
Abstract: RATIONALE AND OBJECTIVES Chronic hypersensitivity pneumonitis (cHP) is a heterogeneous condition, where both small airway involvement and fibrosis may simultaneously occur. Computer-aided analysis of CT lung imaging is increasingly used to improve tissue characterization in… read more here.
Keywords: convolutional neural; chronic hypersensitivity; neural network; hypersensitivity pneumonitis ... See more keywords
A systematically derived exposure assessment instrument for Chronic Hypersensitivity Pneumonitis.
Sign Up to like & getrecommendations! Published in 2020 at "Chest"
DOI: 10.1016/j.chest.2019.12.018
Abstract: BACKGROUND Chronic hypersensitivity pneumonitis (CHP) is an immune mediated interstitial lung disease, caused by inhalational exposure to environmental antigens, resulting in parenchymal fibrosis. By definition, a diagnosis of CHP assumes a history of antigen exposure,… read more here.
Keywords: assessment instrument; exposure assessment; chp; exposure ... See more keywords
Insights on chronic hypersensitivity pneumonitis' treatment: Factors associated with a favourable response to azathioprine.
Sign Up to like & getrecommendations! Published in 2021 at "Life sciences"
DOI: 10.1016/j.lfs.2021.119274
Abstract: BACKGROUND The use of immunosuppressive and antifibrotic agents for the treatment of chronic hypersensitivity pneumonitis (CHP) appears promising, but there is still no evidence supporting the clinical decision regarding the implementation of each specific pharmacological… read more here.
Keywords: associated favourable; response; treatment; chronic hypersensitivity ... See more keywords
Clinical utility of a standardized chronic hypersensitivity pneumonitis exposure questionnaire
Sign Up to like & getrecommendations! Published in 2022 at "Respirology"
DOI: 10.1111/resp.14404
Abstract: Identification of an exposure is integral to the diagnosis, management, and prognostication of chronic hypersensitivity pneumonitis (CHP). Standardized questionnaires may aid in the identification of exposures, however, there currently are no evidence‐based patient‐validated questionnaires available.… read more here.
Keywords: hypersensitivity pneumonitis; exposure questionnaire; exposure; chronic hypersensitivity ... See more keywords
Prognostic accuracy of a peripheral blood transcriptome signature in chronic hypersensitivity pneumonitis
Sign Up to like & getrecommendations! Published in 2021 at "Thorax"
DOI: 10.1136/thoraxjnl-2020-214790
Abstract: The prognostic value of peripheral blood mononuclear cell (PBMC) expression profiles, when used in patients with chronic hypersensitivity pneumonitis (CHP), as an adjunct to traditional clinical assessment is unknown. RNA-seq analysis on PBMC from 37… read more here.
Keywords: chronic hypersensitivity; peripheral blood; hypersensitivity pneumonitis;
Rare Protein-altering Telomere-related Gene Variants in Patients with Chronic Hypersensitivity Pneumonitis.
Sign Up to like & getrecommendations! Published in 2019 at "American journal of respiratory and critical care medicine"
DOI: 10.1164/rccm.201902-0360oc
Abstract: RATIONALE Rare genetic variants in telomere-related genes have been identified in familial, idiopathic, and rheumatoid arthritis-associated pulmonary fibrosis. Short peripheral blood leukocyte (PBL) telomere length predicts poor outcomes in chronic hypersensitivity pneumonitis (CHP). OBJECTIVES Determine… read more here.
Keywords: telomere length; chronic hypersensitivity; rare protein; telomere related ... See more keywords
Chronic hypersensitivity pneumonitis; an enigmatic and frequently fatal disease
Sign Up to like & getrecommendations! Published in 2020 at "European Respiratory Review"
DOI: 10.1183/16000617.0177-2020
Abstract: In the current issue of the European Respiratory Review, Creamer and Barratt [1] review prognostic factors in chronic hypersensitivity pneumonitis (cHP). Their work provides a state-of-the-art overview on the topic; but in doing so, highlights… read more here.
Keywords: chronic hypersensitivity; hypersensitivity pneumonitis; fatal disease;
Use of leflunomide in patients with chronic hypersensitivity pneumonitis
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DOI: 10.1186/s12890-020-01227-2
Abstract: Background Prednisone has been shown to reverse lung function declines in hypersensitivity pneumonitis patients without established fibrosis. Second line immunosuppressants like azathioprine and mycophenolate mofetil have a steroid sparing effect and improve DLCO. There is… read more here.
Keywords: use leflunomide; chronic hypersensitivity; hypersensitivity; hypersensitivity pneumonitis ... See more keywords