Altered Redox Balance in the Development of Chronic Hypoxia-induced Pulmonary Hypertension.
Sign Up to like & getrecommendations! Published in 2017 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-319-63245-2_7
Abstract: Normally, the pulmonary circulation is maintained in a low-pressure, low-resistance state with little resting tone. Pulmonary arteries are thin-walled and rely heavily on pulmonary arterial distension and recruitment for reducing pulmonary vascular resistance when cardiac… read more here.
Keywords: chronic hypoxia; pulmonary hypertension; resistance; development ... See more keywords
Molecular Characterization of Equilibrative Nucleoside Transporters in the Rat Carotid Body and Their Regulation by Chronic Hypoxia.
Sign Up to like & getrecommendations! Published in 2018 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-319-91137-3_5
Abstract: The mammalian carotid body (CB) is the main peripheral arterial chemoreceptor organ that is excited by decreases in blood PO2 (hypoxia) and increases in blood PCO2/H+. An increase in CB afferent carotid sinus nerve (CSN)… read more here.
Keywords: chronic hypoxia; molecular characterization; hypoxia; carotid body ... See more keywords
Degradation of the mitochondrial complex I assembly factor TMEM126B under chronic hypoxia
Sign Up to like & getrecommendations! Published in 2018 at "Cellular and Molecular Life Sciences"
DOI: 10.1007/s00018-018-2779-y
Abstract: Cell stress such as hypoxia elicits adaptive responses, also on the level of mitochondria, and in part is mediated by the hypoxia-inducible factor (HIF) 1α. Adaptation of mitochondria towards acute hypoxic conditions is reasonably well… read more here.
Keywords: chronic hypoxia; factor; assembly; hypoxia ... See more keywords
[Chronic hypoxia and cardiovascular risk : Clinical significance of different forms of hypoxia].
Sign Up to like & getrecommendations! Published in 2018 at "Herz"
DOI: 10.1007/s00059-017-4570-5
Abstract: It is of fundamental importance to differentiate whether chronic hypoxia occurs intermittently or persistently. While chronic intermittent hypoxia (CIH) is found typically in patients with obstructive sleep apnea (OAS), chronic persistent hypoxia (CPH) is typically… read more here.
Keywords: hypoxia; chronic hypoxia; hypoxia cardiovascular; cardiovascular risk ... See more keywords
High protein intake promotes the adaptation to chronic hypoxia in zebrafish (Danio rerio)
Sign Up to like & getrecommendations! Published in 2021 at "Aquaculture"
DOI: 10.1016/j.aquaculture.2021.736356
Abstract: Abstract Chronic hypoxia is a common environmental stress factor in aquaculture. Many researchers have illustrated the physiological and metabolic changes under chronic hypoxia, but there are few studies to evaluate the relationship between dietary nutrients… read more here.
Keywords: hypoxia; hypoxia zebrafish; high protein; protein intake ... See more keywords
Cardiac performance with chronic hypoxia: mechanisms regulating stroke volume
Sign Up to like & getrecommendations! Published in 2019 at "Current Opinion in Physiology"
DOI: 10.1016/j.cophys.2018.12.007
Abstract: When humans are exposed to high altitude hypoxia for a sustained period, the cardiac stroke volume is reduced. The changes in cardiac performance seen at high altitude are a result of complex and concomitant changes… read more here.
Keywords: cardiac performance; stroke volume; volume; chronic hypoxia ... See more keywords
Memantine ameliorates cognitive impairment induced by exposure to chronic hypoxia environment at high altitude by inhibiting excitotoxicity.
Sign Up to like & getrecommendations! Published in 2021 at "Life sciences"
DOI: 10.1016/j.lfs.2020.119012
Abstract: AIMS Memantine is a non-competitive antagonist of glutamatergic NMDA receptor that is mainly used in the treatment of Alzheimer's disease. The excitatory toxicity mediated by glutamate via glutamatergic receptor signals is considered to be one… read more here.
Keywords: chronic hypoxia; cognitive impairment; environment; exposure ... See more keywords
De novo transcriptome assembly of the amphipod Gammarus chevreuxi exposed to chronic hypoxia
Sign Up to like & getrecommendations! Published in 2017 at "Marine Genomics"
DOI: 10.1016/j.margen.2017.01.006
Abstract: Abstract Environmental hypoxia is becoming more prevalent in aquatic environments due to eutrophication and climate change. While the ecological and physiological responses of marine animals to hypoxia have received considerable attention, the molecular responses remain… read more here.
Keywords: chronic hypoxia; novo transcriptome; gammarus chevreuxi; hypoxia ... See more keywords
Chloroquine attenuates chronic hypoxia‐induced testicular damage via suppressing endoplasmic reticulum stress and apoptosis in experimental rat model
Sign Up to like & getrecommendations! Published in 2022 at "Clinical and Experimental Pharmacology and Physiology"
DOI: 10.1111/1440-1681.13669
Abstract: Chronic hypoxia negatively affects male fertility by causing pathological changes in male reproductive system. However, underlying mechanisms of this damage are unknown. Chloroquine (CLQ) is an anti‐inflammatory agent that is widely used in the treatment… read more here.
Keywords: hypoxia induced; damage; testicular damage; induced testicular ... See more keywords
Regulatory B cells protect against chronic hypoxia‐induced pulmonary hypertension by modulating the Tfh/Tfr immune balance
Sign Up to like & getrecommendations! Published in 2022 at "Immunology"
DOI: 10.1111/imm.13589
Abstract: Hypoxia‐induced pulmonary hypertension (HPH) is a progressive and lethal disease characterized by the uncontrolled proliferation of pulmonary artery smooth muscle cells (PASMCs) and obstructive vascular remodelling. Previous research demonstrated that Breg cells were involved in… read more here.
Keywords: pulmonary hypertension; chronic hypoxia; hypoxia; breg cells ... See more keywords
Myocardial ischemic tolerance in rats subjected to endurance exercise training during adaptation to chronic hypoxia.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of applied physiology"
DOI: 10.1152/japplphysiol.00671.2016
Abstract: Chronic hypoxia and exercise are natural stimuli that confer sustainable cardioprotection against ischemia-reperfusion (I/R) injury, but it is unknown whether they can act in synergy to enhance ischemic resistance. Inflammatory response mediated by tumor necrosis… read more here.
Keywords: chronic hypoxia; cnh; hypoxia; exercise ... See more keywords