Clonally expanded PD-1-expressing T cells are enriched in synovial fluid of juvenile idiopathic arthritis patients.
Sign Up to like & getrecommendations! Published in 2023 at "European journal of immunology"
DOI: 10.1002/eji.202250162
Abstract: Juvenile idiopathic arthritis (JIA) is the most common chronic rheumatic condition in childhood. Disease etiology remains largely unknown, however a key role in JIA pathogenesis is surely mediated by T cells. T lymphocytes activity is… read more here.
Keywords: clonally expanded; chronic inflammation; idiopathic arthritis; juvenile idiopathic ... See more keywords
Osteocalcin does not influence acute or chronic inflammation in human vascular cells
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.29231
Abstract: Some human observational studies have suggested an anti‐inflammatory role of osteocalcin (OCN). An inflammatory protocol using interferon‐γ and tumor necrosis factor‐α (10 ng/ml) was employed to examine the acute (24 hr) and chronic (144 hr) effects of uncarboxylated… read more here.
Keywords: influence acute; osteocalcin influence; inflammation; chronic inflammation ... See more keywords
Role of heat shock proteins in aging and chronic inflammatory diseases.
Sign Up to like & getrecommendations! Published in 2021 at "GeroScience"
DOI: 10.1007/s11357-021-00394-2
Abstract: Advanced age is associated with a decline in response to stress. This contributes to the establishment of chronic inflammation, one of the hallmarks of aging and age-related disease. Heat shock proteins (HSP) are determinants of… read more here.
Keywords: age related; age; pathology; chronic inflammation ... See more keywords
RAGE-TLR Crosstalk Sustains Chronic Inflammation in Neurodegeneration
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Neurobiology"
DOI: 10.1007/s12035-017-0419-4
Abstract: Chronic inflammatory reactions are consistenly present in neurodegeneration of Alzheimer type and are considered important factors that accelerate progression of the disease. Receptors of innate immunity participate in triggering and driving inflammatory reactions. For example,… read more here.
Keywords: tlr crosstalk; inflammation; chronic inflammation; rage tlr ... See more keywords
3061 – PU.1 ENFORCES QUIESCENCE AND LIMITS HEMATOPOIETIC STEM CELL EXPANSION DURING CHRONIC INFLAMMATION
Sign Up to like & getrecommendations! Published in 2020 at "Experimental Hematology"
DOI: 10.1016/j.exphem.2020.09.078
Abstract: Hematopoietic stem cell (HSC) quiescence supports lifelong blood regeneration and guards against pre-leukemic clonal expansion. Acute exposure to the pro-inflammatory cytokine interleukin (IL)-1 drives myeloid cell production and HSC cell cycle entry. However, HSC return… read more here.
Keywords: hsc; cell; chronic inflammation; quiescence ... See more keywords
Role of thiocyanate in the repair of myeloperoxidase-derived thiol oxidation during chronic inflammation
Sign Up to like & getrecommendations! Published in 2018 at "Free Radical Biology and Medicine"
DOI: 10.1016/j.freeradbiomed.2018.10.249
Abstract: Myeloperoxidase is a vital component of the human immune system, producing the potent oxidant hypochlorous acid (HOCl), to kill bacteria and other invading pathogens. However, an overproduction of HOCl causes oxidative stress and damage to… read more here.
Keywords: oxidation; chronic inflammation; scn; hocl ... See more keywords
Phosphoesterase complex modulates microflora and chronic inflammation in rats with alcoholic fatty liver disease.
Sign Up to like & getrecommendations! Published in 2020 at "Life sciences"
DOI: 10.1016/j.lfs.2020.118509
Abstract: Phosphoesterase complex (Pho), a major active component of barley malt, has been demonstrated to be clinically effective in relieving alcoholic fatty liver disease (AFLD), and several lines of evidence have suggested that microbial dysbiosis, caused… read more here.
Keywords: alcoholic fatty; fatty liver; phosphoesterase complex; inflammation ... See more keywords
ILC in chronic inflammation, cancer and targeting with biologicals.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular aspects of medicine"
DOI: 10.1016/j.mam.2021.100963
Abstract: Since their discovery, Innate Lymphoid Cells (ILC) have emerged as important effector cells, serving multiple roles in maintaining tissue homeostasis and responding to tissue insults. As such, dysregulations of their function and distribution have been… read more here.
Keywords: chronic inflammation; cancer targeting; inflammation cancer; ilc chronic ... See more keywords
A multifaceted analysis of social stressors and chronic inflammation
Sign Up to like & getrecommendations! Published in 2018 at "SSM - Population Health"
DOI: 10.1016/j.ssmph.2018.09.005
Abstract: Chronic stress has been linked to negative health outcomes, including increased inflammation, which can be measured by high-sensitivity C-reactive protein (CRP). Prior research has focused almost exclusively on relationships between individual social and demographic stressors… read more here.
Keywords: analysis social; high crp; multifaceted analysis; inflammation ... See more keywords
Resolving a chronic inflammation mystery
Sign Up to like & getrecommendations! Published in 2017 at "Nature Medicine"
DOI: 10.1038/nm.4384
Abstract: Using interleukin (IL)-9-deficient mice, Rauber and colleagues unveil a crucial role for group 2 innate lymphoid cells (ILC2s) in the resolution phase of arthritic inflammation, opening up new therapeutic avenues for chronic inflammatory disease. read more here.
Keywords: medicine; inflammation; chronic inflammation; inflammation mystery ... See more keywords
The brain and immune system prompt energy shortage in chronic inflammation and ageing
Sign Up to like & getrecommendations! Published in 2017 at "Nature Reviews Rheumatology"
DOI: 10.1038/nrrheum.2017.172
Abstract: Sequelae frequently seen in patients with chronic inflammatory diseases, such as fatigue, depressed mood, sleep alterations, loss of appetite, muscle wasting, cachectic obesity, bone loss and hypertension, can be the result of energy shortages caused… read more here.
Keywords: chronic inflammation; immune system; energy;