Chronic Insomnia: Treatment with Transcranial Alternating Current Stimulation
Sign Up to like & getrecommendations! Published in 2021 at "Brain Stimulation"
DOI: 10.1016/j.brs.2021.05.007
Abstract: Chronic insomnia is one of the most common types of sleep disorder [1]. The incidence of chronic insomnia in the general population ranges from 4% to 48% [2]. Because of its high prevalence and increased… read more here.
Keywords: insomnia; stimulation; treatment; chronic insomnia ... See more keywords
A novel cognitive behavioral treatment for patients with chronic insomnia: A pilot experimental study.
Sign Up to like & getrecommendations! Published in 2018 at "Complementary therapies in medicine"
DOI: 10.1016/j.ctim.2018.01.015
Abstract: OBJECTIVES Chronic insomnia (CI) is a common sleep disorder linked to stress and various ubiquitous stress-related disorders (e.g. cardiovascular and mental diseases). Previous experimental studies exploring the effects of stress management in CI have confirmed… read more here.
Keywords: medicine; experimental study; chronic insomnia; study ... See more keywords
Changes in subcortical shape and cognitive function in patients with chronic insomnia.
Sign Up to like & getrecommendations! Published in 2017 at "Sleep medicine"
DOI: 10.1016/j.sleep.2017.04.002
Abstract: OBJECTIVE The aim of this study was to examine morphological changes in subcortical structures via surface-based analysis and to correlate local shape changes with cognitive function. METHODS We analyzed subcortical brain morphology and compared the… read more here.
Keywords: changes subcortical; shape; chronic insomnia; patients chronic ... See more keywords
Alteration of gamma-aminobutyric acid in the left dorsolateral prefrontal cortex of individuals with chronic insomnia: a combined transcranial magnetic stimulation-magnetic resonance spectroscopy study.
Sign Up to like & getrecommendations! Published in 2022 at "Sleep medicine"
DOI: 10.1016/j.sleep.2022.03.003
Abstract: OBJECTIVE To investigate changes in the level of gamma-aminobutyric acid (GABA) in the left dorsolateral prefrontal cortex (DLPFC) of patients with chronic insomnia treated with real repetitive transcranial magnetic stimulation (rTMS) as compared to sham-rTMS,… read more here.
Keywords: gamma aminobutyric; spectroscopy; chronic insomnia; rtms ... See more keywords
Altered ultradian cortisol rhythmicity as a potential neurobiologic substrate for chronic insomnia.
Sign Up to like & getrecommendations! Published in 2018 at "Sleep medicine reviews"
DOI: 10.1016/j.smrv.2018.03.003
Abstract: Chronic insomnia is highly prevalent and associated with significant morbidity (i.e., confers risk for multiple psychiatric and medical disorders, such as depression and hypertension). Therefore, it is essential to identify factors that perpetuate this disorder.… read more here.
Keywords: cortisol; insomnia; ultradian cortisol; chronic insomnia ... See more keywords
Medial parietal alpha-frequency transcranial alternating current stimulation for chronic insomnia: a randomized sham-controlled trial
Sign Up to like & getrecommendations! Published in 2025 at "Psychological Medicine"
DOI: 10.1017/s0033291725000625
Abstract: Abstract Background Patients with chronic insomnia are characterized by alterations in default mode network and alpha oscillations, for which the medial parietal cortex (MPC) is a key node and thus a potential target for interventions.… read more here.
Keywords: insomnia; alpha frequency; connectivity; chronic insomnia ... See more keywords
Comparative Effectiveness of an FDA-Authorized Digital Therapeutic to Medications and Cognitive Behavioral Therapy Treating Chronic Insomnia in Adults
Sign Up to like & getrecommendations! Published in 2022 at "CNS Spectrums"
DOI: 10.1017/s1092852922000384
Abstract: Abstract Introduction Chronic insomnia affects the physical and mental health, quality of life, and productivity of 6 to 10% of the adult population (15-25 million U.S. adults). Available treatments include guideline-recommended first-line cognitive behavioral therapy… read more here.
Keywords: digital therapeutic; cbt; insomnia; chronic insomnia ... See more keywords
Reduced Healthcare Resource Utilization in Patients With Chronic Insomnia 24 Months After Treatment With Digital CBT-I: A Matched-Control Study
Sign Up to like & getrecommendations! Published in 2023 at "CNS Spectrums"
DOI: 10.1017/s1092852923001529
Abstract: Abstract Introduction This analysis examined the impact of a digital therapeutic for treating chronic insomnia (currently marketed as Somryst®, at the time called Sleep Healthy Using The internet [SHUTi]) on healthcare resource use (HCRU) by… read more here.
Keywords: chronic insomnia; patients chronic; healthcare resource; lower irr ... See more keywords
State-specific thalamic dysregulation in chronic insomnia revealed by dynamic edge-centric functional connectivity
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-08408-1
Abstract: To investigate dynamic cortical-thalamocortical-subcortical network dysregulation in chronic insomnia (CI) using dynamic edge functional connectivity (deFC) analysis, focusing on thalamus-mediated transient connectivity states and their clinical correlations. 30 CI patients and 32 matched healthy controls… read more here.
Keywords: connectivity; chronic insomnia; state; functional connectivity ... See more keywords
Cortical activation and functional connectivity during verbal fluency task in patients with chronic insomnia: a multi-channel fNIRS study.
Sign Up to like & getrecommendations! Published in 2025 at "Scientific reports"
DOI: 10.1038/s41598-025-29365-9
Abstract: Chronic insomnia disorder (CID) is associated with verbal fluency deficits linked to abnormal prefrontal activation. This multichannel functional near-infrared spectroscopy (fNIRS) study compared prefrontal hemodynamic responses and functional connectivity during verbal fluency tasks (VFT) in… read more here.
Keywords: activation; verbal fluency; connectivity; chronic insomnia ... See more keywords
Exploratory GABAa-informed control network modulates hyperarousal brain dynamics in chronic insomnia
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DOI: 10.1038/s42003-025-08439-4
Abstract: Chronic insomnia disorder is characterized by hyperarousal, a heightened cortical activation pattern that disrupts normal sleep. While hyperarousal has been linked to altered brain state dynamics, the underlying neurobiological mechanisms remain poorly understood, particularly regarding… read more here.
Keywords: brain; gabaa; chronic insomnia; state ... See more keywords