Efficacy and safety of eltrombopag in persistent and newly diagnosed ITP in clinical practice
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DOI: 10.1007/s12185-017-2275-4
Abstract: Eltrombopag is safe and effective in primary chronic ITP. However, lack of clinical trials avoids a clear demonstration of its utility in newly diagnosed and persistent ITP. Our aim here is to report Spanish results… read more here.
Keywords: newly diagnosed; diagnosed itp; chronic itp; efficacy ... See more keywords
High dose dexamethasone as an alternative rescue therapy for active bleeding in children with chronic ITP: clinical and immunological effects
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DOI: 10.1080/09537104.2018.1530347
Abstract: Abstract High-dose dexamethasone (HD-DXM) is debated as a second-line therapy for chronic Immune thrombocytopenia (ITP) in children. The aim of this study is to evaluate the efficacy and safety of HD-DXM as an emergency therapy… read more here.
Keywords: high dose; chronic itp; dose dexamethasone; children chronic ... See more keywords
Revisiting the management of chronic ITP; a randomized controlled clinical trial
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DOI: 10.1080/09537104.2020.1738367
Abstract: Abstract The balance between therapy effectiveness and economic efficiency in chronic immune thrombocytopenia (ITP) becomes more confusing. This single-center open label randomized controlled trial evaluates the effectiveness and safety of hydroxychloroquine in chronic ITP patients… read more here.
Keywords: trial; randomized controlled; response; revisiting management ... See more keywords
Is There a Need to Look for Antithyroid Antibodies in Children With Immune Thrombocytopenia?
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DOI: 10.1097/mph.0000000000002083
Abstract: To the Editor: I read with interest the paper on polyautoimmunity in childhood immune thrombocytopenia (ITP) by Kamioka et al1 but I would like to challenge the suggestion of looking for antithyroid antibodies in children… read more here.
Keywords: chronic itp; antibodies children; immune thrombocytopenia; antithyroid antibodies ... See more keywords
Role of Ca2+, Calnexin and Calreticulin in Platelet from Adult Patients with Chronic Immune Thrombocytopenic Purpura
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DOI: 10.2147/ijgm.s347301
Abstract: Background Adult chronic immune thrombocytopenia (chronic ITP) is a common autoimmune hemorrhagic disease characterized by decreased platelet production and increased platelet destruction, leading to thrombocytopenia. In this study, Ca2+, calnexin (CNX) and calreticulin (CRT) within… read more here.
Keywords: patients chronic; adult patients; chronic itp; platelet ... See more keywords