Targeted blocking of miR328 lysosomal degradation with alkalized exosomes sensitizes the chronic leukemia cells to imatinib
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DOI: 10.1007/s00253-019-10127-3
Abstract: Imatinib resistance remains the biggest hurdle for the treatment of chronic myeloid leukemia (CML), with the underlying mechanisms not fully understood. In this study, we found that miR328 significantly and strikingly decreased among other miRNA… read more here.
Keywords: chronic leukemia; leukemia cells; alkalized exosomes; mir328 ... See more keywords
Pemphigus and hematologic malignancies: A populationâbased study of 11,859 patients
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DOI: 10.1016/j.jaad.2017.11.039
Abstract: Background: The association of nonparaneoplastic pemphigus with comorbid hematologic malignancies has yet to be established. Objective: To estimate the association between pemphigus and the common types of hematologic malignancies. Methods: A crossâsectional study was conducted… read more here.
Keywords: chronic leukemia; study; hematologic malignancies; association ... See more keywords