Effect of Spinal Manipulative and Mobilization Therapies in Young Adults With Mild to Moderate Chronic Low Back Pain
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DOI: 10.1001/jamanetworkopen.2020.12589
Abstract: This randomized clinical trial evaluates the effectiveness of spinal manipulation and spinal mobilization compared with a placebo at reducing pain and disability among young adults with mild to moderate chronic low back pain. read more here.
Keywords: adults mild; young adults; low back; chronic low ... See more keywords
Cross-Sectional Trends in Potentially Low-Value Services for Commercially Insured Patients With Chronic Low Back Pain
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DOI: 10.1001/jamanetworkopen.2021.47178
Abstract: This cross-sectional study characterizes trends in services for commercially insured patients with chronic low back pain from 2011 to 2019. read more here.
Keywords: insured patients; patients chronic; chronic low; cross sectional ... See more keywords
Effect of Medication Optimization vs Cognitive Behavioral Therapy Among US Veterans With Chronic Low Back Pain Receiving Long-term Opioid Therapy
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.42533
Abstract: Key Points Question What are the most effective pain treatments for patients prescribed opioids? Findings In this randomized clinical trial of 261 veterans with chronic low back pain prescribed opioids, pain improvement on the Brief… read more here.
Keywords: veterans chronic; chronic low; therapy; pain ... See more keywords
Acupuncture for Chronic Low Back Pain in Older Adults
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DOI: 10.1001/jamanetworkopen.2025.31348
Abstract: Key Points Question Is acupuncture needling (both a standard acupuncture course and additional maintenance sessions) an effective treatment for older adults with chronic low back pain (CLBP)? Findings In this randomized clinical trial that included… read more here.
Keywords: low back; acupuncture; chronic low; back pain ... See more keywords
Mindfulness vs Cognitive Behavioral Therapy for Chronic Low Back Pain Treated With Opioids
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DOI: 10.1001/jamanetworkopen.2025.3204
Abstract: Key Points Question What is the comparative effectiveness of mindfulness-based therapy (MBT) and standard-of-care cognitive behavioral therapy (CBT) among adults with opioid-treated chronic low back pain (CLBP)? Findings In this randomized clinical trial of 770… read more here.
Keywords: therapy; low back; pain; behavioral therapy ... See more keywords
Analgesic effect of clobazam in chronic low‐back pain but not in experimentally induced pain
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DOI: 10.1002/ejp.1032
Abstract: Chronic pain is frequently associated with hypersensitivity of the nervous system, and drugs that increase central inhibition are therefore a potentially effective treatment. Benzodiazepines are potent modulators of GABAergic neurotransmission and are known to exert… read more here.
Keywords: back pain; low back; chronic low; effect ... See more keywords
Brief intervention, physical exercise and cognitive behavioural group therapy for patients with chronic low back pain (The CINS trial)
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DOI: 10.1002/ejp.1041
Abstract: Cognitive‐behavioural treatments (CBT) and physical group exercise (PE) have both shown promising effects in reducing disability and increasing work participation among chronic low back pain (CLBP) patients. A brief cognitive intervention (BI) has previously been… read more here.
Keywords: back pain; cognitive behavioural; group; low back ... See more keywords
Does the heritability of chronic low back pain depend on how the condition is assessed?
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DOI: 10.1002/ejp.1448
Abstract: Although the influence of genetics on chronic low back pain (LBP) has been previously examined, few studies have investigated whether the impact of genetic factors on LBP depends on how the condition is assessed. read more here.
Keywords: back pain; low back; chronic low; condition assessed ... See more keywords
Opioids for chronic low back pain: An updated systematic review and meta‐analysis of efficacy, tolerability and safety in randomized placebo‐controlled studies of at least 4 weeks of double‐blind duration
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DOI: 10.1002/ejp.1519
Abstract: This updated systematic review evaluated the efficacy, tolerability and safety of opioids compared to placebo in non‐malignant chronic low back pain. read more here.
Keywords: updated systematic; tolerability safety; systematic review; low back ... See more keywords
Oxytocin modulates intrinsic neural activity in patients with chronic low back pain
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DOI: 10.1002/ejp.1543
Abstract: Modulation of pain perception by oxytocin (OXT) has attracted increased scientific and clinical interest. Neural mechanisms underlying these effects are poorly understood. In this study, we aimed to investigate the effects of intranasally applied OXT… read more here.
Keywords: neural activity; activity patients; chronic low; patients chronic ... See more keywords
Generalizability of harm and pain expectations after exposure in chronic low back pain patients.
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DOI: 10.1002/ejp.1604
Abstract: BACKGROUND Exposure treatments are shown to be effective in reducing pain-related fear and the perceived harmfulness of physical activities. However, due to the fragility of extinction its stability is questionable. We investigated the generalizability of… read more here.
Keywords: exposure; chronic low; pain expectations; harm pain ... See more keywords