Effect of Spinal Manipulative and Mobilization Therapies in Young Adults With Mild to Moderate Chronic Low Back Pain
Sign Up to like & getrecommendations! Published in 2020 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2020.12589
Abstract: This randomized clinical trial evaluates the effectiveness of spinal manipulation and spinal mobilization compared with a placebo at reducing pain and disability among young adults with mild to moderate chronic low back pain. read more here.
Keywords: adults mild; young adults; low back; chronic low ... See more keywords
Cross-Sectional Trends in Potentially Low-Value Services for Commercially Insured Patients With Chronic Low Back Pain
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2021.47178
Abstract: This cross-sectional study characterizes trends in services for commercially insured patients with chronic low back pain from 2011 to 2019. read more here.
Keywords: insured patients; patients chronic; chronic low; cross sectional ... See more keywords
Effect of Medication Optimization vs Cognitive Behavioral Therapy Among US Veterans With Chronic Low Back Pain Receiving Long-term Opioid Therapy
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.42533
Abstract: Key Points Question What are the most effective pain treatments for patients prescribed opioids? Findings In this randomized clinical trial of 261 veterans with chronic low back pain prescribed opioids, pain improvement on the Brief… read more here.
Keywords: veterans chronic; chronic low; therapy; pain ... See more keywords
Analgesic effect of clobazam in chronic low‐back pain but not in experimentally induced pain
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Pain"
DOI: 10.1002/ejp.1032
Abstract: Chronic pain is frequently associated with hypersensitivity of the nervous system, and drugs that increase central inhibition are therefore a potentially effective treatment. Benzodiazepines are potent modulators of GABAergic neurotransmission and are known to exert… read more here.
Keywords: back pain; low back; chronic low; effect ... See more keywords
Brief intervention, physical exercise and cognitive behavioural group therapy for patients with chronic low back pain (The CINS trial)
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Pain"
DOI: 10.1002/ejp.1041
Abstract: Cognitive‐behavioural treatments (CBT) and physical group exercise (PE) have both shown promising effects in reducing disability and increasing work participation among chronic low back pain (CLBP) patients. A brief cognitive intervention (BI) has previously been… read more here.
Keywords: back pain; cognitive behavioural; group; low back ... See more keywords
Does the heritability of chronic low back pain depend on how the condition is assessed?
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Pain"
DOI: 10.1002/ejp.1448
Abstract: Although the influence of genetics on chronic low back pain (LBP) has been previously examined, few studies have investigated whether the impact of genetic factors on LBP depends on how the condition is assessed. read more here.
Keywords: back pain; low back; chronic low; condition assessed ... See more keywords
Opioids for chronic low back pain: An updated systematic review and meta‐analysis of efficacy, tolerability and safety in randomized placebo‐controlled studies of at least 4 weeks of double‐blind duration
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Pain"
DOI: 10.1002/ejp.1519
Abstract: This updated systematic review evaluated the efficacy, tolerability and safety of opioids compared to placebo in non‐malignant chronic low back pain. read more here.
Keywords: updated systematic; tolerability safety; systematic review; low back ... See more keywords
Oxytocin modulates intrinsic neural activity in patients with chronic low back pain
Sign Up to like & getrecommendations! Published in 2020 at "European Journal of Pain"
DOI: 10.1002/ejp.1543
Abstract: Modulation of pain perception by oxytocin (OXT) has attracted increased scientific and clinical interest. Neural mechanisms underlying these effects are poorly understood. In this study, we aimed to investigate the effects of intranasally applied OXT… read more here.
Keywords: neural activity; activity patients; chronic low; patients chronic ... See more keywords
Generalizability of harm and pain expectations after exposure in chronic low back pain patients.
Sign Up to like & getrecommendations! Published in 2020 at "European journal of pain"
DOI: 10.1002/ejp.1604
Abstract: BACKGROUND Exposure treatments are shown to be effective in reducing pain-related fear and the perceived harmfulness of physical activities. However, due to the fragility of extinction its stability is questionable. We investigated the generalizability of… read more here.
Keywords: exposure; chronic low; pain expectations; harm pain ... See more keywords
Examining what factors mediate treatment effect in chronic low back pain: A mediation analysis of a Cognitive Functional Therapy clinical trial
Sign Up to like & getrecommendations! Published in 2020 at "European Journal of Pain"
DOI: 10.1002/ejp.1624
Abstract: Cognitive Functional Therapy (CFT) is a physiotherapist‐led individualized intervention for people with people with non‐specific chronic low back pain (CLBP), involving biopsychosocial pain education, graded movement exposure and lifestyle coaching. read more here.
Keywords: back pain; functional therapy; cognitive functional; low back ... See more keywords
Apoptosis, rather than neurogenesis, induces significant hippocampal‐dependent learning and memory impairment in chronic low Cd2+ exposure
Sign Up to like & getrecommendations! Published in 2022 at "Environmental Toxicology"
DOI: 10.1002/tox.23445
Abstract: Cadmium (Cd), a ubiquitous toxic heavy metal, with the intractable trait of low degradation, can induce multiple organ damage. Whereas, far less is known about its neurotoxicity and the specific mechanism in the chronic low… read more here.
Keywords: apoptosis; learning memory; chronic low; cd2 ... See more keywords