Effective Spinal Cord Stimulation Does Not Improve Caregiver Burden in Patients With Chronic Neuropathic Pain. Results of the CARESTIM‐Study
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DOI: 10.1002/ejp.70122
Abstract: Spinal cord stimulation (SCS) is a well‐established treatment for chronic neuropathic and ischaemic pain. Although patient‐reported outcomes have increasingly gained recognition, the impact of SCS on informal caregivers—an equally important consideration—remains underexplored. This study aims… read more here.
Keywords: chronic neuropathic; pain; spinal cord; cord stimulation ... See more keywords
An Injectable Hydrogel for Treatment of Chronic Neuropathic Pain.
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DOI: 10.1002/mabi.202100529
Abstract: Current treatments for chronic neuropathic pain often fall short. A small-molecular compound ZL006 can suppress N-Methyl-D-aspartate receptor (NMDAR)-mediated neuropathic pain behaviors without blocking essential NMDAR function and brings new hope for neuropathic pain therapy. The… read more here.
Keywords: injectable hydrogel; zl006; pain; neuropathic pain ... See more keywords
[Pharmacotherapy of chronic neuropathic pain].
Sign Up to like & getrecommendations! Published in 2019 at "Der Internist"
DOI: 10.1007/s00108-019-0627-2
Abstract: Chronic neuropathic pain has a prevalence of 6.9-10% in the general population. The current recommendations for treatment are presented based on a literature search. Neuropathic pain requires the use of co-analgesic, antidepressant, anticonvulsant drugs and topical agents… read more here.
Keywords: chronic neuropathic; etiology; pharmacotherapy chronic; neuropathic pain ... See more keywords
Repetitive Transcranial Magnetic Stimulation for Treating Chronic Neuropathic Pain: a Systematic Review
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DOI: 10.1007/s11916-021-00960-5
Abstract: Given pharmacological interventions’ limited efficacy and abundance of its adverse effects, the repetitive transcranial magnetic stimulation (rTMS) is considered a viable non-invasive option for managing chronic neuropathic pain of different origins with promising outcomes. The… read more here.
Keywords: chronic neuropathic; stimulation; repetitive transcranial; transcranial magnetic ... See more keywords
The Development of Translational Biomarkers as a Tool for Improving the Understanding, Diagnosis and Treatment of Chronic Neuropathic Pain
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DOI: 10.1007/s12035-017-0492-8
Abstract: Chronic neuropathic pain (CNP) is one of the most significant unmet clinical needs in modern medicine. Alongside the lack of effective treatments, there is a great deficit in the availability of objective diagnostic methods to… read more here.
Keywords: chronic neuropathic; diagnosis; translational biomarkers; neuropathic pain ... See more keywords
Cannabis-Based Medicines and Medical Cannabis for Chronic Neuropathic Pain
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DOI: 10.1007/s40263-021-00879-w
Abstract: Neuropathic pain represents a broad category of pain syndromes that include a wide variety of peripheral and central disorders. The overall prevalence of neuropathic pain in the general population is reported to be between 7… read more here.
Keywords: chronic neuropathic; cannabis based; based medicines; neuropathic pain ... See more keywords
Efficacy of Internet-Delivered Mindfulness for Improving Depression in Caregivers of People With Spinal Cord Injuries and Chronic Neuropathic Pain: A Randomized Controlled Feasibility Trial.
Sign Up to like & getrecommendations! Published in 2019 at "Archives of physical medicine and rehabilitation"
DOI: 10.1016/j.apmr.2018.08.182
Abstract: OBJECTIVES To explore the feasibility and efficacy of web-based mindfulness training for carers of people with spinal cord injury (SCI). DESIGN Randomized controlled feasibility study with 3-month follow-up. SETTING Community setting. PARTICIPANTS Spouses or family… read more here.
Keywords: chronic neuropathic; caregivers people; feasibility; neuropathic pain ... See more keywords
Activation of parabrachial nucleus - ventral tegmental area pathway underlies the comorbid depression in chronic neuropathic pain in mice
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DOI: 10.1016/j.celrep.2021.109936
Abstract: Summary Depression symptoms are often found in patients suffering from chronic pain, a phenomenon that is yet to be understood mechanistically. Here, we systematically investigate the cellular mechanisms and circuits underlying the chronic-pain-induced depression behavior.… read more here.
Keywords: chronic neuropathic; depression; tegmental area; ventral tegmental ... See more keywords
Time course of the response to navigated repetitive transcranial magnetic stimulation at 10 Hz in chronic neuropathic pain
Sign Up to like & getrecommendations! Published in 2018 at "Neurological Research"
DOI: 10.1080/01616412.2018.1453636
Abstract: ABSTRACT Objective This prospective study evaluated the time to response and outcomes of navigated repetitive transcranial magnetic stimulation (TMS) at a frequency of 10 Hz in patients with chronic neuropathic pain. Methods This prospective study… read more here.
Keywords: chronic neuropathic; stimulation; navigated repetitive; time ... See more keywords
Intrathecal injection of dexmedetomidine ameliorates chronic neuropathic pain via the modulation of MPK3/ERK1/2 in a mouse model of chronic neuropathic pain
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DOI: 10.1080/01616412.2019.1672391
Abstract: ABSTRACT Objective: Despite the application of dexmedetomidine (DEX) as a perioperative adjuvant in local analgesia, the exact analgesic mechanism underpinning chronic neuropathic pain (CNP) awaits our elucidation. Methods: We investigated the molecular mechanisms of the… read more here.
Keywords: chronic neuropathic; dex; injection; neuropathic pain ... See more keywords
A Multicriteria Decision Analysis Comparing Pharmacotherapy for Chronic Neuropathic Pain, Including Cannabinoids and Cannabis-Based Medical Products.
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DOI: 10.1089/can.2020.0129
Abstract: Background: Pharmacological management of chronic neuropathic pain (CNP) still represents a major clinical challenge. Collective harnessing of both the scientific evidence base and clinical experience (of clinicians and patients) can play a key role in… read more here.
Keywords: pain; chronic neuropathic; neuropathic pain; decision ... See more keywords