Chronic orofacial pain
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Neural Transmission"
DOI: 10.1007/s00702-020-02157-3
Abstract: While pain chronicity in general has been defined as pain lasting for more than 3 months, this definition is not useful in orofacial pain (OFP) and headache (HA). Instead, chronicity in OFP and HA is… read more here.
Keywords: definition; chronic orofacial; orofacial pain; epidemiology ... See more keywords
“I Still Suffer Every Second of Every Day”: A Qualitative Analysis of the Challenges of Living with Chronic Orofacial Pain
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Pain Research"
DOI: 10.2147/jpr.s372469
Abstract: Objective Chronic orofacial pain is prevalent and debilitating. Psychological and social factors place a heavy burden on this population but are often overlooked. Here, we offer the first comprehensive qualitative conceptualization of the challenges of… read more here.
Keywords: challenges living; orofacial pain; analysis; living chronic ... See more keywords
NMDARs mediate peripheral and central sensitization contributing to chronic orofacial pain
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2022.999509
Abstract: Peripheral and central sensitizations of the trigeminal nervous system are the main mechanisms to promote the development and maintenance of chronic orofacial pain characterized by allodynia, hyperalgesia, and ectopic pain after trigeminal nerve injury or… read more here.
Keywords: peripheral central; chronic orofacial; orofacial pain; pain ... See more keywords
The chronification mechanism of orofacial inflammatory pain: Facilitation by GPER1 and microglia in the rostral ventral medulla
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Molecular Neuroscience"
DOI: 10.3389/fnmol.2022.1078309
Abstract: Background Chronic orofacial pain is a common and incompletely defined clinical condition. The role of G protein-coupled estrogen receptor 1 (GPER1) as a new estrogen receptor in trunk and visceral pain regulation is well known.… read more here.
Keywords: rostral ventral; gper1; orofacial pain; pain ... See more keywords
Gut Bless Your Pain—Roles of the Gut Microbiota, Sleep, and Melatonin in Chronic Orofacial Pain and Depression
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DOI: 10.3390/biomedicines10071528
Abstract: Background. Increased attention has been paid to the gut–brain axis recently, but little is known so far regarding how this translates into pain susceptibility. Aim. The aim of this review is to determine whether gastroenterological… read more here.
Keywords: pain depression; orofacial pain; depression; pain ... See more keywords
Reduced Endocannabinoid Tone in Saliva of Chronic Orofacial Pain Patients
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DOI: 10.3390/molecules27144662
Abstract: Background: the endocannabinoid system (ECS) participates in many physiological and pathological processes including pain generation, modulation, and sensation. Its involvement in chronic orofacial pain (OFP) in general, and the reflection of its involvement in OFP… read more here.
Keywords: orofacial pain; chronic ofp; lower levels; pain ... See more keywords