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   Articles with "chronic oxidative" as a keyword



Rapamycin Removes Damaged Mitochondria and Protects Human Trabecular Meshwork (TM-1) Cells from Chronic Oxidative Stress

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recommendations! Published in 2019 at "Molecular Neurobiology"

DOI: 10.1007/s12035-019-1559-5

Abstract: Glaucoma is a chronic optic neuropathy that could lead to permanent vision loss. Primary open-angle glaucoma (POAG) is the most common type of glaucoma, with elevated intraocular pressure (IOP) as a major risk factor. IOP… read more here.

Keywords: trabecular meshwork; chronic oxidative; human trabecular; stress ... See more keywords

Chronic Oxidative Stress and Comorbidities in the HIV-1 Transgenic Rat

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recommendations! Published in 2019 at "Microscopy and Microanalysis"

DOI: 10.1017/s1431927619006536

Abstract: The pathogenesis of AIDS comorbidities are the result of a number of mechanisms that can ultimately lead to cell death. One such mechanism for which there is accumulating evidence is chronic oxidative stress (COS). The… read more here.

Keywords: pathology; chronic oxidative; stress comorbidities; cos ... See more keywords

Compensation for chronic oxidative stress in ALADIN null mice

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recommendations! Published in 2018 at "Biology Open"

DOI: 10.1242/bio.030742

Abstract: ABSTRACT Mutations in the AAAS gene coding for the nuclear pore complex protein ALADIN lead to the autosomal recessive disorder triple A syndrome. Triple A patients present with a characteristic phenotype including alacrima, achalasia and… read more here.

Keywords: chronic oxidative; triple syndrome; mice; aladin null ... See more keywords

Hesperetin Increases Lifespan and Antioxidant Ability Correlating with IIS, HSP, mtUPR, and JNK Pathways of Chronic Oxidative Stress in Caenorhabditis elegans

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recommendations! Published in 2024 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms252313148

Abstract: Hesperetin (Hst) is a common citrus fruit flavonoid with antioxidant, anti-inflammatory, and anti-neurodegenerative effects. To explore the antioxidant and anti-aging effects and mechanisms of Hst, we induced chronic oxidative stress in Caenorhabditis elegans (C. elegans)… read more here.

Keywords: oxidative stress; chronic oxidative; stress caenorhabditis; jnk pathways ... See more keywords

Chronic Oxidative Stress and Stress Granule Formation in UBQLN2 ALS Neurons: Insights into Neuronal Degeneration and Potential Therapeutic Targets

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recommendations! Published in 2024 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms252413448

Abstract: The pathogenesis of neurodegenerative diseases results from the interplay between genetic and environmental factors. Aging and chronic oxidative stress are critical contributors to neurodegeneration. UBQLN2, a ubiquitin-related protein, aids in protein degradation and protects against… read more here.

Keywords: stress granule; stress; oxidative stress; chronic oxidative ... See more keywords