Chronic persistent surgical pain is strongly associated with COMT alleles in patients undergoing cardiac surgery with median sternotomy
Sign Up to like & getrecommendations! Published in 2020 at "General Thoracic and Cardiovascular Surgery"
DOI: 10.1007/s11748-020-01321-6
Abstract: Objectives Catechol- O -methyl transferase (COMT), a catechol-dependent enzyme, plays pivotal role in the development of pain. In different ethnic populations, it is associated with chronic persistent surgical pain (CPSP). In this context, the present… read more here.
Keywords: surgery; chronic persistent; persistent surgical; cpsp ... See more keywords
Chikungunya virus and autoimmunity
Sign Up to like & getrecommendations! Published in 2017 at "Current Opinion in Rheumatology"
DOI: 10.1097/bor.0000000000000396
Abstract: Purpose of review Chikungunya virus (CHIKV) is a mosquito-borne alphavirus. Fever, rash and severe arthralgia are the hallmarks of chikungunya fever (CHIKF), the disease caused by this virus. The acute course of the disease usually… read more here.
Keywords: chronic persistent; disease; course; chikungunya virus ... See more keywords
Safety and efficacy of long-term treatment of chronic/persistent ITP with eltrombopag: final results of the EXTEND study.
Sign Up to like & getrecommendations! Published in 2017 at "Blood"
DOI: 10.1182/blood-2017-04-748707
Abstract: In phase 2/3 trials, eltrombopag treatment of 6 months or less in patients with chronic/persistent immune thrombocytopenia (ITP) increased platelet counts and reduced bleeding. The open-label EXTEND study evaluated long-term safety and efficacy of eltrombopag… read more here.
Keywords: chronic persistent; long term; treatment; adverse events ... See more keywords
Dysregulated Arginine Metabolism in Young Patients with Chronic Persistent Asthma and in Human Bronchial Epithelial Cells
Sign Up to like & getrecommendations! Published in 2021 at "Nutrients"
DOI: 10.3390/nu13114116
Abstract: Background: Recent metabolomics studies have found circulatory metabolism alterations in patients with asthma, indicating that altered metabolites played a significant role in asthma. However, the regulatory mechanisms in asthma, especially in young chronic persistent asthma… read more here.
Keywords: chronic persistent; metabolism; young patients; patients chronic ... See more keywords