Ponatinib after failure of second‐generation tyrosine kinase inhibitor in resistant chronic‐phase chronic myeloid leukemia
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Hematology"
DOI: 10.1002/ajh.26686
Abstract: Ponatinib, the only third‐generation pan‐BCR::ABL1 inhibitor with activity against all known BCR::ABL1 mutations including T315I, has demonstrated deep and durable responses in patients with chronic‐phase chronic myeloid leukemia (CP‐CML) resistant to prior second‐generation (2G) TKI… read more here.
Keywords: chronic myeloid; leukemia; generation; phase chronic ... See more keywords
Ponatinib as second-line treatment in chronic phase chronic myeloid leukemia patients in real-life practice
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DOI: 10.1007/s00277-018-3337-2
Abstract: Scarce information is available on the use of ponatinib as second-line treatment in chronic phase chronic myeloid leukemia (CP-CML) patients resistant and/or intolerant to prior tyrosine kinase inhibitor (TKI) therapy. We collected data from 29… read more here.
Keywords: line; chronic phase; treatment; line treatment ... See more keywords
Intracranial granulocytic sarcoma as the first presentation of chronic myeloid leukemia in chronic phase
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DOI: 10.1007/s11060-017-2541-6
Abstract: metamyelocytes and a few eosinophilic cells. Immunohistochemistry (IHC) showed that the tumor was strongly positive for leukocyte common antigen CD45 and pan myeloid marker CD15. Only occasional myeloblasts expressed CD117 (Fig. 1). This demonstrates that… read more here.
Keywords: phase; granulocytic sarcoma; chronic phase; myeloid leukemia ... See more keywords
LncRNA CCAT2 expression at diagnosis predicts imatinib response in chronic phase chronic myeloid leukemia patients.
Sign Up to like & getrecommendations! Published in 2022 at "Leukemia research"
DOI: 10.1016/j.leukres.2022.106838
Abstract: Long noncoding RNAs (lncRNAs) are identified as key players in the initiation, development, and prognosis of chronic myeloid leukemia (CML). Some lncRNAs are expected to serve as diagnostic biomarkers, predictors of clinical outcomes and therapeutic… read more here.
Keywords: expression; ccat2; response; chronic phase ... See more keywords
THE EARLY EVALUATION OF HEART RATE VARIATION AFTER CATHETER ABLATION PREDICTS THE RECURRENCE ON CHRONIC PHASE IN PATIENTS WITH ATRIAL FIBRILLATION
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the American College of Cardiology"
DOI: 10.1016/s0735-1097(18)30923-9
Abstract: The heart rate variation (HRV) modified by catheter ablation (CA) procedure might impact the chronic phase recurrence in patients with atrial fibrillation (AF). We retrospectively accessed continuous 209 patients (77 females, age: 68.1±8.0, 88 with… read more here.
Keywords: atrial fibrillation; rate variation; chronic phase; catheter ablation ... See more keywords
Serum erythropoietin levels in essential thrombocythemia: phenotypic and prognostic correlates
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DOI: 10.1038/s41408-018-0157-5
Abstract: Serum erythropoietin (EPO) level below the normal reference range is widely accepted as a minor diagnostic criterion for polycythemia vera (PV) and has retained its value in the revised 2016 World Health Organization (WHO) classification… read more here.
Keywords: chronic phase; levels essential; epo; serum erythropoietin ... See more keywords
The effects of socioeconomic and geographic factors on chronic phase long-term survival after stroke in South Korea
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DOI: 10.1038/s41598-022-08025-2
Abstract: The stroke incidence has increased rapidly in South Korea, calling for a national-wide system for long-term stroke management. We investigated the effects of socioeconomic status (SES) and geographic factors on chronic phase survival after stroke.… read more here.
Keywords: survival; chronic phase; geographic factors; factors chronic ... See more keywords
Effects of computer-based cognitive rehabilitation on working memory in patients with acquired brain injury in the chronic phase, a pilot-study
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DOI: 10.1080/02699052.2022.2034965
Abstract: ABSTRACT Background Working memory impairment is common in patients in the chronic phase after acquired brain injury (ABI), and there is a need to develop efficacious rehabilitation methods. This trial explored the effects of two… read more here.
Keywords: working memory; support; brain injury; memory ... See more keywords
Outcomes of adolescents and young adults with chronic-phase chronic myeloid leukaemia treated with tyrosine kinase inhibitors
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DOI: 10.1080/07853890.2022.2069280
Abstract: Abstract Introduction Few studies have reported the outcomes of adolescents and young adults (AYAs) with chronic-phase chronic myeloid leukaemia (CML-CP) on tyrosine kinase inhibitors (TKIs). Materials and methods We retrospectively analysed the clinical features, treatment… read more here.
Keywords: outcomes adolescents; adolescents young; chronic myeloid; young adults ... See more keywords
Biopsychosocial factors associated with the state of disability after hemiparesis in the chronic phase of stroke: exploratory analysis based on the International Classification of Functioning, Disability and Health.
Sign Up to like & getrecommendations! Published in 2023 at "Disability and rehabilitation"
DOI: 10.1080/09638288.2023.2196444
Abstract: OBJECTIVE To identify the main biopsychosocial factors associated with disability level after stroke using the International Classification of Functioning, Disability and Health (ICF) model. METHODS A cross-sectional study was conducted with chronic stroke survivors. Disability… read more here.
Keywords: health; activities participation; return work; disability ... See more keywords
Upfront nilotinib therapy among patients with chronic myeloid leukemia in chronic phase
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DOI: 10.1080/14656566.2017.1282697
Abstract: I have read with great interest the paper by Saydam et al. [1], reporting results of a company sponsored multicenter study from Turkey which evaluated the efficacy and safety of nilotinib 300 mg twice daily… read more here.
Keywords: chronic phase; myeloid leukemia; chronic myeloid; leukemia chronic ... See more keywords