Tofacitinib for the treatment of chronic pouchitis: A pilot study
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DOI: 10.1002/ueg2.12683
Abstract: Abstract Background & Aims Up to 15% of ulcerative colitis (UC) patients with an ileo‐anal pouch will develop chronic or antibiotic refractory pouchitis. We aimed to evaluate the efficacy and safety of tofacitinib in these… read more here.
Keywords: treatment; pouchitis; pilot study; chronic pouchitis ... See more keywords
Clinical Discrimination of Chronic Pouchitis After Ileal Pouch-Anal Anastomosis in Patients with Ulcerative Colitis
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DOI: 10.1007/s11605-020-04842-w
Abstract: We aimed to identify predictive factors for the development of chronic pouchitis after ileal pouch-anal anastomosis in patients with ulcerative colitis. Three hundred eighty-seven patients who underwent ileal pouch-anal anastomosis for diagnosis of ulcerative colitis… read more here.
Keywords: pouchitis; pouchitis patients; ileal pouch; ulcerative colitis ... See more keywords
P682 A Retrospective Comparison of Different Treatment Modalities in Patients with Chronic Pouchitis
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DOI: 10.1093/ecco-jcc/jjad212.0812
Abstract: Chronic pouchitis affects ~30% of patients post total colectomy with ileal pouch anal anastomosis (IPAA) surgery. Treatment with anti-TNF, anti-integrin α4β7, anti-IL-12/23, or Crohn's disease exclusion diet (CDED), have shown promise in different studies. We… read more here.
Keywords: treatment; response rates; mpdai response; response ... See more keywords
OP32 Identifying clusters of antibiotic use patterns after the first episode of pouchitis in a population-based cohort
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DOI: 10.1093/ecco-jcc/jjae190.0032
Abstract: An estimated 17% of patients will develop chronic pouchitis after ileal pouch-anal anastomosis (IPAA) for ulcerative colitis (UC), however little is known about antibiotic prescribing patterns in the immediate period after an initial episode of… read more here.
Keywords: ipaa; initial episode; pouchitis; episode pouchitis ... See more keywords
Diet and Microbiota Modulation for Chronic Pouchitis: Evidence, Challenges, and Opportunities
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DOI: 10.3390/nu16244337
Abstract: Chronic pouchitis occurs in about 50% of patients undergoing a restorative proctocolectomy for ulcerative colitis. This affection represents a significant therapeutic challenge, particularly for symptomatic patients who do not respond to antibiotic treatments and biologic… read more here.
Keywords: evidence; diet microbiota; chronic pouchitis; microbiota modulation ... See more keywords