[Therapy for chronic pruritus-light at the end of a long tunnel?]
Sign Up to like & getrecommendations! Published in 2020 at "Der Internist"
DOI: 10.1007/s00108-020-00837-6
Abstract: Chronic pruritus (CP) is a highly prevalent, difficult-to-treat, and burdensome condition. Today, multiple topical and systemic therapy concepts are available for the treatment of CP. Current guidelines recommend, besides topical treatments, the use of a vast array… read more here.
Keywords: therapy chronic; pruritus; pruritus light; chronic pruritus ... See more keywords
Botanical Complementary and Alternative Medicine for Pruritus: a Systematic Review
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DOI: 10.1007/s13671-017-0200-y
Abstract: Purpose of ReviewComplementary and alternative medicine (CAM) is widely used by patients who suffer from chronic pruritus, but there is little data on the efficacy or antipruritic mechanism of these interventions. This review assesses the… read more here.
Keywords: medicine; alternative medicine; botanical complementary; pruritus ... See more keywords
Inhibition of temperature-sensitive TRPV3 channel by two natural isochlorogenic acid isomers for alleviation of dermatitis and chronic pruritus
Sign Up to like & getrecommendations! Published in 2021 at "Acta Pharmaceutica Sinica B"
DOI: 10.1016/j.apsb.2021.08.002
Abstract: Abstract Genetic gain-of-function mutations of warm temperature-sensitive transient receptor potential vanilloid 3 (TRPV3) channel cause Olmsted syndrome characterized by severe itching and keratoderma, indicating that pharmacological inhibition of TRPV3 may hold promise for therapy of… read more here.
Keywords: isochlorogenic acid; channel; chronic pruritus; trpv3 channel ... See more keywords
Selective serotonin reuptake inhibitors for the treatment of chronic pruritus
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Dermatological Treatment"
DOI: 10.1080/09546634.2018.1456639
Abstract: Chronic pruritus is defined as itch lasting 6 weeks or longer. Although chronic pruritus has a significant burden of disease, there are currently no FDA approved treatments specifically targeting p... read more here.
Keywords: selective serotonin; serotonin reuptake; treatment; pruritus ... See more keywords
Substance P and neurokinin 1 receptor are new targets for the treatment of chronic pruritus
Sign Up to like & getrecommendations! Published in 2019 at "British Journal of Dermatology"
DOI: 10.1111/bjd.18025
Abstract: Chronic pruritus is a distressing symptom associated with various dermatological conditions and systemic diseases. Current treatment options are often inadequate, resulting in impaired quality of life for many patients. An understanding of the underlying mechanisms… read more here.
Keywords: neurokinin receptor; substance neurokinin; receptor new; treatment ... See more keywords
Itch in skin of colour: a multicentre cross‐sectional study
Sign Up to like & getrecommendations! Published in 2021 at "British Journal of Dermatology"
DOI: 10.1111/bjd.20403
Abstract: Chronic pruritus is associated with a significant reduction in quality of life. Patients with chronic pruritus endorse similar levels of quality of life impairment as patients with stroke1 , and present with greater rates of… read more here.
Keywords: cross sectional; skin colour; multicentre cross; itch skin ... See more keywords
Relations between a standardized experimental stressor and cutaneous sensory function in patients with chronic pruritus and healthy controls: an experimental case–control study
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the European Academy of Dermatology and Venereology"
DOI: 10.1111/jdv.15030
Abstract: While chronic pruritus (CP) is a frequent symptom, many aspects of its underlying pathophysiological mechanisms still need elucidation. Research on sensory cutaneous function and on the influence of stress has been conducted mainly in patients… read more here.
Keywords: experimental stressor; standardized experimental; pruritus; chronic pruritus ... See more keywords
Prevalence and potential risk factors of chronic pruritus among community middle‐aged and older population in Beijing, China
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the European Academy of Dermatology and Venereology"
DOI: 10.1111/jdv.18041
Abstract: Chronic pruritus is a common problem among older adults, with a significant impact on their quality of life. However, it is under‐studied epidemiologically, especially among Chinese older adults. read more here.
Keywords: chronic pruritus; potential risk; prevalence potential; risk factors ... See more keywords
Chronic pruritus in multiple sclerosis and clinical correlates
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DOI: 10.1111/jdv.18561
Abstract: To date, little is known about the prevalence of itch in multiple sclerosis (MS) and its characteristics. read more here.
Keywords: chronic pruritus; multiple sclerosis; sclerosis; pruritus multiple ... See more keywords
Pruritus assessment tools for 6 to 7-year-old children: KidsItchyQoL and ItchyQuant.
Sign Up to like & getrecommendations! Published in 2021 at "Pediatric dermatology"
DOI: 10.1111/pde.14563
Abstract: BACKGROUND/OBJECTIVES Measures of pruritus severity and quality of life (QoL) are necessary for the development of therapeutics for children with chronic pruritus. In children, questionnaires need to be developed for specific age groups given the… read more here.
Keywords: kidsitchyqol itchyquant; pruritus assessment; pruritus; pruritus severity ... See more keywords
Systemic causes of non-dermatologic chronic pruritus in the pediatric population and their management: An unexplored area.
Sign Up to like & getrecommendations! Published in 2021 at "Pediatric dermatology"
DOI: 10.1111/pde.14596
Abstract: Chronic pruritus associated with systemic diseases in the pediatric population has been infrequently addressed in the literature. This review focuses on chronic pruritus presenting without cutaneous manifestations. Common systemic etiologies include diseases with hepatic, renal,… read more here.
Keywords: dermatology; pruritus; chronic pruritus; pediatric population ... See more keywords