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Published in 2022 at "Clinical and Translational Allergy"
DOI: 10.1002/clt2.12168
Abstract: Abstract Background Hypoxia is considered a key factor in the pathogenesis of chronic rhinosinusitis with nasal polyps (CRSwNP). However, the specific mechanism driving polypogenesis under hypoxic conditions is unclear. This study aimed to explore hypoxia‐induced… read more here.
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Published in 2023 at "Clinical and Translational Allergy"
DOI: 10.1002/clt2.12269
Abstract: Abstract Background To compare the safety and efficacy between endoscopic sinus surgery and different biologics in treating chronic rhinosinusitis with nasal polyps in adults by reviewing the existing clinical trials. Methods Data extraction and risk… read more here.
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Published in 2020 at "Immunity"
DOI: 10.1002/iid3.349
Abstract: The pathophysiology and temporal dynamics of affected tissues in chronic rhinosinusitis (CRS) remain poorly understood. Here, we present a multiomics‐based time‐series assessment of nasal polyp biopsies from three patients with CRS, assessing natural variability over… read more here.
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Published in 2023 at "Laryngoscope Investigative Otolaryngology"
DOI: 10.1002/lio2.1026
Abstract: Chronic rhinosinusitis (CRS), a common disease in otorhinolaryngology, seriously affects the life quality of patients. The existing therapy has certain limitations, and it is very urgent to deeply explore the pathogenesis and classification of CRS.… read more here.
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Published in 2023 at "Laryngoscope Investigative Otolaryngology"
DOI: 10.1002/lio2.1027
Abstract: Chronic rhinosinusitis (CRS) is a heterogeneous disease, which can be subdivided into CRS with (CRSwNP) or without (CRSsNP) nasal polyps. An intractable form of CRSwNP that is associated with an eosinophil‐dominant inflammatory cell infiltration (eosinophilic… read more here.
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Published in 2019 at "Laryngoscope Investigative Otolaryngology"
DOI: 10.1002/lio2.299
Abstract: Chronic rhinosinusitis (CRS) has an impact on health‐related quality of life (HRQOL). The objective of this study was to examine generic and disease‐specific HRQOL and symptoms in CRS patients with (CRSwNP) and without (CRSsNP) nasal… read more here.
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Published in 2021 at "Laryngoscope Investigative Otolaryngology"
DOI: 10.1002/lio2.523
Abstract: Chronic rhinosinusitis (CRS) is a disease with significant impacts at both a societal and personal level. There has been an increase in emphasis on patient‐centered care and patient outcomes, with value becoming a commonplace concept… read more here.
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Published in 2021 at "Laryngoscope Investigative Otolaryngology"
DOI: 10.1002/lio2.524
Abstract: Topical sinonasal rinse therapies may alter the local microbiome and improve disease control in chronic rhinosinusitis (CRS). The objective of this study was to examine microbiome changes in post‐surgical CRS patients when rinsing with commercially… read more here.
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Published in 2022 at "Laryngoscope Investigative Otolaryngology"
DOI: 10.1002/lio2.733
Abstract: The extent to which sinonasal symptoms impact the likelihood of major depressive disorders in chronic rhinosinusitis patients with nasal polyposis (CRSwNP) remains incompletely characterized. In this study, we sought to determine whether individual symptom clusters… read more here.