Melatonin upregulates BMAL1 to attenuate chronic sleep deprivation‐related cognitive impairment by alleviating oxidative stress
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DOI: 10.1002/brb3.2836
Abstract: To investigate the mechanism underlying the regulatory effect of melatonin on chronic sleep deprivation‐related cognitive impairment. read more here.
Keywords: deprivation related; chronic sleep; sleep deprivation; cognitive impairment ... See more keywords
Effects of chronic sleep restriction on the neuro-phenotypes of Ctnnd2 knockout mice.
Sign Up to like & getrecommendations! Published in 2023 at "Brain and behavior"
DOI: 10.1002/brb3.3075
Abstract: INTRODUCTION Sleep abnormalities are highly correlated with neurodevelopmental disorders, such as intellectual disability, attention deficit hyperactivity disorder, and autism spectrum disorders (ASD). The severity of behavioral abnormalities is correlated with the presence of sleep abnormalities.… read more here.
Keywords: sleep restriction; chronic sleep; ctnnd2 knockout; effects chronic ... See more keywords
Soy isoflavones protects against cognitive deficits induced by chronic sleep deprivation via alleviating oxidative stress and suppressing neuroinflammation
Sign Up to like & getrecommendations! Published in 2022 at "Phytotherapy Research"
DOI: 10.1002/ptr.7354
Abstract: Mounting evidence suggests that there is a close association between chronic sleep deprivation (CSD) and cognitive deficits. The animal model of CSD‐induced cognitive deficits is commonly used to seek potential treatments. Soy isoflavones (SI) have… read more here.
Keywords: chronic sleep; sleep deprivation; cognitive deficits; csd ... See more keywords
Identification of salivary microRNA profiles in male mouse model of chronic sleep disorder.
Sign Up to like & getrecommendations! Published in 2022 at "Stress"
DOI: 10.1080/10253890.2022.2156783
Abstract: Chronic sleep disorders (CSD) comprise a potential risk factor for metabolic and cardiovascular diseases, obesity and stroke. Thus, the identification of biomarkers for CSD is an important step in the early prevention of metabolic dysfunctions… read more here.
Keywords: chronic sleep; identification; microrna; zt0 ... See more keywords
0254 The Effects of Chronic Sleep Restriction on Multiple Object Tracking
Sign Up to like & getrecommendations! Published in 2020 at "Sleep"
DOI: 10.1093/sleep/zsaa056.252
Abstract: The ability to simultaneously track numerous moving objects in the presence of irrelevant stimuli is essential for successfully carrying out a variety of tasks. Sleep loss impairs neurocognitive functioning and, as a result, attentional processing… read more here.
Keywords: hours sleep; sleep restriction; object tracking; multiple object ... See more keywords
0429 Chronic Sleep Disturbance Causes Cognitive Impairment and Alzheimer’S Disease-Like Neuropathology
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DOI: 10.1093/sleep/zsaa056.426
Abstract: Sleep disturbance is among the most common clinical problem and possesses a significant concern for the geriatric population. Recently, increasing evidence has indicated that disturbed sleep may not only affect neuropsychological functions, but also contribute… read more here.
Keywords: cognitive impairment; sleep disturbance; chronic sleep; 0429 chronic ... See more keywords
0089 Chronic sleep disruption increases amyloid beta deposition and gliosis in the 5xFAD mouse model
Sign Up to like & getrecommendations! Published in 2023 at "SLEEP"
DOI: 10.1093/sleep/zsad077.0089
Abstract: Recent studies have found that mid-life sleep disruption is associated with the development of Alzheimer’s disease-related neuropathology, including the deposition of amyloid beta. Yet, the mechanism connecting sleep disruption, particularly over chronic timescales, and downstream… read more here.
Keywords: amyloid beta; chronic sleep; sleep disruption; disruption ... See more keywords
Short Daytime Naps Briefly Attenuate Objectively Measured Sleepiness Under Chronic Sleep Restriction
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DOI: 10.1093/sleep/zsx118
Abstract: Study Objectives Napping is a useful countermeasure to the negative effects of acute sleep loss on alertness. The efficacy of naps to recover from chronic sleep loss is less well understood. Methods Following 2 baseline… read more here.
Keywords: daytime naps; sleep restriction; sleepiness; chronic sleep ... See more keywords
Response to chronic sleep restriction, extension, and subsequent total sleep deprivation in humans: adaptation or preserved sleep homeostasis?
Sign Up to like & getrecommendations! Published in 2018 at "SLEEP"
DOI: 10.1093/sleep/zsy078
Abstract: Sleep is regulated by a homeostatic process which in the two-process model of human sleep regulation is represented by electroencephalogram slow-wave activity (SWA). Many studies of acute manipulation of wake duration have confirmed the precise… read more here.
Keywords: restriction; sleep restriction; response; chronic sleep ... See more keywords
No loss of orexin/hypocretin, melanin‐concentrating hormone or locus coeruleus noradrenergic neurons in a rat model of chronic sleep restriction
Sign Up to like & getrecommendations! Published in 2021 at "European Journal of Neuroscience"
DOI: 10.1111/ejn.15412
Abstract: Chronic sleep restriction (CSR) is common in modern society, adversely affecting cognitive performance and health. Yet how it impacts neurons regulating sleep remains unclear. Several studies using mice reported substantial losses of wake‐active orexin/hypocretin and… read more here.
Keywords: orexin; protocol; noradrenergic neurons; chronic sleep ... See more keywords
Adverse interaction effects of chronic and acute sleep deficits on spatial working memory but not on verbal working memory or declarative memory
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Sleep Research"
DOI: 10.1111/jsr.13225
Abstract: The accumulation of chronic sleep deficits combined with acute sleep loss is common in shift workers and increases the risk of errors and accidents. We investigated single and combined effects of chronic and acute sleep… read more here.
Keywords: group; acute sleep; working memory; chronic sleep ... See more keywords