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Published in 2022 at "Pediatric hematology and oncology"
DOI: 10.1080/08880018.2022.2148030
Abstract: Strokes affect up to 10% of children with sickle-cell disease (SCD). The most commonly used strategy to prevent a first-time stroke or its recurrence is to perform periodic red blood cell transfusions. This article aims…
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Keywords:
cell;
chronic transfusion;
cell disease;
quality life ... See more keywords
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Published in 2019 at "Transfusion"
DOI: 10.1111/trf.15453
Abstract: R ed blood cell (RBC) transfusion is the cornerstone of therapy for sickle cell disease (SCD). The genetic mutation in SCD results in the production of hemoglobin (Hb) S. HbS polymerizes when deoxygenated and deforms…
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Keywords:
transfusion;
chronic transfusion;
transfusion therapy;
sickle cell ... See more keywords
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Published in 2020 at "Blood"
DOI: 10.1182/blood-2020-140828
Abstract: Introduction: Irradiation of blood products is necessary to prevent transfusion-associated graft-versus-host disease (TA-GVHD) for patients at risk of this fatal transfusion complication. Despite the implementation of protocols to identify patients at risk of TA-GVHD, missed…
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Keywords:
universal irradiation;
irradiation;
policy;
time ... See more keywords