Effects of Chronic Treatment of Haloperidol and Clozapine on Levels of G-Protein Subunits in Rat Striatum
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Molecular Neuroscience"
DOI: 10.1007/bf03380139
Abstract: Chronic administration of typical neuroleptic drugs, such as haloperidol, causes the supersensitivity of brain dopamine D2 receptor in striatum and limbic regions, while the atypical neuroleptic clozapine does not. In order to understand the mechanism… read more here.
Keywords: treatment haloperidol; clozapine; chronic treatment; treatment ... See more keywords
Chronic treatment with the antipsychotic drug blonanserin modulates the responsiveness to acute stress with anatomical selectivity
Sign Up to like & getrecommendations! Published in 2020 at "Psychopharmacology"
DOI: 10.1007/s00213-020-05498-9
Abstract: Rationale Patients diagnosed with schizophrenia typically receive life-long treatments with antipsychotic drugs (APDs). However, the impact of chronic APDs treatment on neuroplastic mechanisms in the brain remains largely elusive. Objective Here, we focused on blonanserin,… read more here.
Keywords: chronic treatment; treatment; blonanserin modulates; drug ... See more keywords
Resveratrol Protects Against Vacuous Chewing Movements Induced by Chronic Treatment with Fluphenazine
Sign Up to like & getrecommendations! Published in 2017 at "Neurochemical Research"
DOI: 10.1007/s11064-017-2335-4
Abstract: Typical antipsychotics, which are commonly used to treat schizophrenia, cause motor disorders such as tardive dyskinesia (TD) in humans and orofacial dyskinesia (OD) in rodents. The disease mechanisms as well as treatment effectiveness are still unknown.… read more here.
Keywords: resveratrol; treatment; chronic treatment; induced chronic ... See more keywords
A multi-method assessment of attentional processes in chronic, treatment-resistant depression.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of psychiatric research"
DOI: 10.1016/j.jpsychires.2021.04.030
Abstract: Attentional deficits as well as attentional biases towards negative material are related to major depression and might maintain chronicity. However, studies investigating attentional deficits and attentional biases in chronic, treatment-resistant depressed are lacking. The aim… read more here.
Keywords: treatment resistant; chronic treatment; treatment; resistant depressed ... See more keywords
Influencia del tratamiento con estatinas en una cohorte de pacientes ingresados por COVID-19
Sign Up to like & getrecommendations! Published in 2021 at "Medicina Clinica"
DOI: 10.1016/j.medcli.2021.07.003
Abstract: Aims and objectives: Statins have been proposed as potentially useful agents for modulating the host response in COVID-19. However, solid evidence-based recommendations are still lacking. Our aim was to study the association between statin use… read more here.
Keywords: hospital admission; chronic treatment; treatment; statin ... See more keywords
Chronic treatment with fluoride affects the jejunum: insights from proteomics and enteric innervation analysis
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-21533-4
Abstract: Gastrointestinal symptoms are the first signs of fluoride (F) toxicity. In the present study, the jejunum of rats chronically exposed to F was evaluated by proteomics, as well as by morphological analysis. Wistar rats received… read more here.
Keywords: affects jejunum; fluoride affects; analysis; chronic treatment ... See more keywords
P5440Systolic/diastolic effects of chronic treatment with omecamtiv mecarbil in minipigs with post-myocardial infarction Heart Failure with reduced Ejection Fraction (HFrEF)
Sign Up to like & getrecommendations! Published in 2019 at "European Heart Journal"
DOI: 10.1093/eurheartj/ehz746.0396
Abstract: Omecamtiv mecarbil (OM), a novel myosin ATPase activator, is currently developed for the treatment of Heart Failure with reduced Ejection Fraction (HFrEF). Phase I in healthy volunteers and patients showed that the positive inotropic effect… read more here.
Keywords: heart; chronic treatment; treatment; myocardial infarction ... See more keywords
The anti-tussive effects of an inhaled LABA are maintained after chronic treatment
Sign Up to like & getrecommendations! Published in 2018 at "European Respiratory Journal"
DOI: 10.1183/13993003.congress-2018.pa5261
Abstract: Introduction: Cough is an essential defensive reflex, however excessive/chronic cough is a problematic symptom of respiratory diseases. We have previously shown that inhaled LABA can attenuate cough responses by suppressing airway sensory nerves. As LABAs… read more here.
Keywords: anti tussive; effects inhaled; chronic treatment; tussive effects ... See more keywords
Chronic treatment with paeonol improves endothelial function in mice through inhibition of endoplasmic reticulum stress-mediated oxidative stress
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DOI: 10.1371/journal.pone.0178365
Abstract: Endoplasmic reticulum (ER) stress leads to endothelial dysfunction which is commonly associated in the pathogenesis of several cardiovascular diseases. We explored the vascular protective effects of chronic treatment with paeonol (2'-hydroxy-4'-methoxyacetophenone), the major compound from… read more here.
Keywords: paeonol; chronic treatment; stress; treatment paeonol ... See more keywords
Disruptions in hepatic glucose metabolism are involved in the diminished efficacy after chronic treatment with glucokinase activator
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DOI: 10.1371/journal.pone.0265761
Abstract: Glucokinase activators are regarded as potent candidates for diabetes treatment, however, in clinical studies on patients with type 2 diabetes, a diminishing efficacy was observed after chronic treatment with them. The mechanism of this reduction… read more here.
Keywords: chronic treatment; efficacy; glucokinase activator; diminished efficacy ... See more keywords
Chronic Treatment with Somatostatin Analogues in Recurrent Type 1 Gastric Neuroendocrine Tumors
Sign Up to like & getrecommendations! Published in 2023 at "Biomedicines"
DOI: 10.3390/biomedicines11030872
Abstract: Background: Type 1 gastric neuroendocrine tumors (GC-1) represent an uncommon subtype of neoplasms. Endoscopic resection has been proposed as the treatment of choice; active surveillance may be performed in those smaller than 1 cm, while… read more here.
Keywords: chronic treatment; gastric neuroendocrine; neuroendocrine tumors; type gastric ... See more keywords