Reactivation of human cytomegalovirus inhibits expression of liver fibrosis related cytokines in patients chronically infected with hepatitis C virus genotype 4a.
Sign Up to like & getrecommendations! Published in 2020 at "Microbial pathogenesis"
DOI: 10.1016/j.micpath.2020.104596
Abstract: BACKGROUND The impact of human cytomegalovirus (HCMV) reactivation on the expression pattern of matrix metalloproteinases, their inhibitors and related cytokines during HCV infection poorly understood. METHODS Reactivation of CMV in 95 subjects (75 chronically infected… read more here.
Keywords: related cytokines; reactivation; fibrosis related; human cytomegalovirus ... See more keywords
Development of a Microenvironment-Responsive Hydrogel Promoting Chronically Infected Diabetic Wound Healing through Sequential Hemostatic, Antibacterial, and Angiogenic Activities.
Sign Up to like & getrecommendations! Published in 2022 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.2c02725
Abstract: Microenvironment-responsive hydrogels present high potential in treating refractory wounds due to their capability of on-demand drug release. In this study, a specially designed hydrogel with smart targeting of refractory wound characteristics was designed to treat… read more here.
Keywords: microenvironment responsive; sequential hemostatic; chronically infected; antibacterial angiogenic ... See more keywords
Large-scale viral genome analysis identifies novel clinical associations between hepatitis B virus and chronically infected patients
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-46609-7
Abstract: Despite the high global prevalence of chronic hepatitis B (CHB) infection, datasets covering the whole hepatitis B viral genome from large patient cohorts are lacking, greatly limiting our understanding of the viral genetic factors involved… read more here.
Keywords: large scale; genome analysis; chronically infected; viral genome ... See more keywords
Therapy of a Chronically Infected Total Femur Prothesis in a 40-year-old Patient.
Sign Up to like & getrecommendations! Published in 2022 at "Zeitschrift fur Orthopadie und Unfallchirurgie"
DOI: 10.1055/a-1754-0051
Abstract: We report a case of a patient who was treated in 1999 at the age of 19 years with a proximal femur replacement due to Ewing sarcoma. After several infection-associated exchange procedures, the patient presented… read more here.
Keywords: total femur; infected total; patient; femur prothesis ... See more keywords
Susceptibility to 3BNC117 and 10-1074 in ART suppressed chronically infected persons
Sign Up to like & getrecommendations! Published in 2023 at "AIDS"
DOI: 10.1097/qad.0000000000003575
Abstract: Objective: The aim of this study was to assess the susceptibility of HIV to two HIV monoclonal antibodies (bnAbs), 3BNC117 and 10-1074, in individuals with chronically antiretroviral therapy (ART) suppressed HIV infection. Design: The susceptibility… read more here.
Keywords: 3bnc117 1074; susceptibility; art suppressed; susceptibility 3bnc117 ... See more keywords
Polymorphic Nature of Human T-Cell Leukemia Virus Type 1 Particle Cores as Revealed through Characterization of a Chronically Infected Cell Line
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Virology"
DOI: 10.1128/jvi.00369-17
Abstract: ABSTRACT Human T-cell leukemia virus type 1 (HTLV-1) is the etiological agent of adult T-cell leukemia (ATL) and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). HTLV-1 cell-to-cell transmission is dependent on the release of infectious virus particles… read more here.
Keywords: htlv; cell line; particle; chronically infected ... See more keywords
Tenofovir may be superior to entecavir for preventing hepatocellular carcinoma and mortality in individuals chronically infected with HBV: a meta-analysis
Sign Up to like & getrecommendations! Published in 2019 at "Gut"
DOI: 10.1136/gutjnl-2019-320326
Abstract: Many studies have demonstrated that monotherapy with tenofovir disoproxil fumarate (TDF) or entecavir (ETV) can reduce the risk of liver complications in individuals chronically infected with HBV (CHB). Unclear is whether one monotherapy is more… read more here.
Keywords: hepatocellular carcinoma; entecavir; tenofovir; individuals chronically ... See more keywords
Risk Assessment of Etanercept in Mice Chronically Infected With Toxoplasma gondii
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2018.02822
Abstract: Toxoplasma gondii (T. gondii) is a zoonotic parasite that severely harms the health of the host. The cysts of T. gondii can reactivate from bradyzoites to tachyzoites, if the individual develops low or defective immunity,… read more here.
Keywords: mice chronically; infection; gondii; chronic infection ... See more keywords
Sequential Appearance and Isolation of a SARS-CoV-2 Recombinant between Two Major SARS-CoV-2 Variants in a Chronically Infected Immunocompromised Patient
Sign Up to like & getrecommendations! Published in 2022 at "Viruses"
DOI: 10.3390/v14061266
Abstract: Genetic recombination is a major evolutionary mechanism among RNA viruses, and it is common in coronaviruses, including those infecting humans. A few SARS-CoV-2 recombinants have been reported to date whose genome harbored combinations of mutations… read more here.
Keywords: cov variants; sequential appearance; recombination; patient ... See more keywords