HPA axis regulation and epigenetic programming of immune-related genes in chronically stressed and non-stressed mid-life women
Sign Up to like & getrecommendations! Published in 2021 at "Brain, Behavior, and Immunity"
DOI: 10.1016/j.bbi.2020.11.027
Abstract: Hypothalamic-pituitary-adrenal (HPA) axis dysregulation has been associated with altered immune function, but the underlying molecular mechanisms are unclear. Epigenetic processes, including DNA methylation, respond to the glucocorticoid end-products of the HPA axis (cortisol in humans)… read more here.
Keywords: chronically stressed; methylation; axis regulation; hpa axis ... See more keywords
Curcumin Alters Neural Plasticity and Viability of Intact Hippocampal Circuits and Attenuates Behavioral Despair and COX-2 Expression in Chronically Stressed Rats
Sign Up to like & getrecommendations! Published in 2017 at "Mediators of Inflammation"
DOI: 10.1155/2017/6280925
Abstract: Curcumin is a major diarylheptanoid component of Curcuma longa with traditional usage for anxiety and depression. It has been known for the anti-inflammatory, antistress, and neurotropic effects. Here we examined curcumin effect in neural plasticity… read more here.
Keywords: stressed rats; viability; neural plasticity; cox expression ... See more keywords
Increased Activity of Hippocampal Antioxidant Enzymes as an Important Adaptive Phenomenon of the Antioxidant Defense System in Chronically Stressed Rats
Sign Up to like & getrecommendations! Published in 2017 at "Acta Veterinaria"
DOI: 10.1515/acve-2017-0043
Abstract: Abstract This study examined the effects of chronic restraint stress (CRS: 2 hours × 14 days) on gene expression of three antioxidant enzymes, copper, zinc superoxide dismutase (SOD 1), manganese superoxide dismutase (SOD 2) and… read more here.
Keywords: stressed rats; antioxidant enzymes; chronically stressed; cat ... See more keywords
Antioxidant defense system in the prefrontal cortex of chronically stressed rats treated with lithium
Sign Up to like & getrecommendations! Published in 2022 at "PeerJ"
DOI: 10.7717/peerj.13020
Abstract: Background This study aimed to investigate the effects of lithium treatment on gene expression and activity of the prefrontal antioxidant enzymes: copper, zinc superoxide dismutase (SOD1), manganes superoxide dismutase (SOD2), catalase (CAT), and glutathione peroxidase… read more here.
Keywords: stressed rats; chronically stressed; antioxidant; lithium ... See more keywords