Nicotinamide supplementation phenocopies SIR2 inactivation by modulating carbon metabolism and respiration during yeast chronological aging
Sign Up to like & getrecommendations! Published in 2017 at "Mechanisms of Ageing and Development"
DOI: 10.1016/j.mad.2016.06.006
Abstract: Nicotinamide (NAM), a form of vitamin B3, is a byproduct and noncompetitive inhibitor of the deacetylation reaction catalyzed by Sirtuins. These represent a family of evolutionarily conserved NAD+-dependent deacetylases that are well-known critical regulators of… read more here.
Keywords: metabolism; nicotinamide supplementation; yeast chronological; respiration ... See more keywords
Exposure of S. cerevisiae to pulsed magnetic field during chronological aging could induce genomic DNA damage.
Sign Up to like & getrecommendations! Published in 2021 at "International journal of environmental health research"
DOI: 10.1080/09603123.2021.1910212
Abstract: This study evaluates the DNA damage induced by pulsed magnetic field (MF) on S. cerevisiae cells exposed during chronological aging. Samples were exposed to 25 Hz pulsed MF (1.5mT, 8 h/day) while cells were aging chronologically. Clonogenic… read more here.
Keywords: dna damage; exposure; cerevisiae; damage ... See more keywords
Systematic transcriptome analysis associated with physiological and chronological aging in Caenorhabditis elegans
Sign Up to like & getrecommendations! Published in 2022 at "Genome Research"
DOI: 10.1101/gr.276515.121
Abstract: Aging is associated with changes in a variety of biological processes at the transcriptomic level, including gene expression. Two types of aging occur during a lifetime: chronological and physiological aging. However, dissecting the difference between… read more here.
Keywords: physiological aging; chronological aging; associated physiological; physiological chronological ... See more keywords
Abstract 1274: Extrinsic photoaging vs intrinsic aging in dermal fibroblasts: Its impact on the microenvironment and melanoma progression
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-1274
Abstract: Melanoma is the deadliest form of skin cancer, with its incidence rising disproportionally to other cancers. Chronological aging is a major risk factor in all types of cancer as it has been shown to drive… read more here.
Keywords: dermal fibroblasts; extrinsic photoaging; melanoma; chronological aging ... See more keywords
Ginsenoside Rg1 Delays Chronological Aging in a Yeast Model via CDC19- and SDH2-Mediated Cellular Metabolism
Sign Up to like & getrecommendations! Published in 2023 at "Antioxidants"
DOI: 10.3390/antiox12020296
Abstract: Ginsenosides, active substances in Panax ginseng C. A. Meyer (ginseng), extend lifespan in multiple species, ameliorate age-associated damage, and limit functional decline in multiple tissues. However, their active components and their molecular mechanisms are largely… read more here.
Keywords: rg1; rg1 delays; chronological aging; sdh2 ... See more keywords
Nicotinamide, Nicotinamide Riboside and Nicotinic Acid—Emerging Roles in Replicative and Chronological Aging in Yeast
Sign Up to like & getrecommendations! Published in 2020 at "Biomolecules"
DOI: 10.3390/biom10040604
Abstract: Nicotinamide, nicotinic acid and nicotinamide riboside are vitamin B3 precursors of NAD+ in the human diet. NAD+ has a fundamental importance for cellular biology, that derives from its essential role as a cofactor of various… read more here.
Keywords: replicative chronological; nicotinamide riboside; chronological aging; nad precursors ... See more keywords