Chronotropic Effects of Milrinone in a Guinea Pig Ex Vivo Model: A Pilot Study to Screen for New Mechanisms of Action
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Cardiovascular Pharmacology"
DOI: 10.1097/fjc.0000000000001675
Abstract: Abstract: Positive inotropic responses upon administration of milrinone, an inhibitor of the phosphodiesterase enzyme (PDE), involve a well-pronounced positive chronotropic effect. Here, we tested whether milrinone evokes this chronotropic response solely by PDE inhibition or… read more here.
Keywords: chronotropic effects; receptor; chronotropic; guinea pig ... See more keywords