A Reasonable Evaluation of Chuanxiong Rhizoma Processing with Wine through Comparative Pharmacokinetic Study of Bioactive Components: Dominant Effect on Middle Cerebral Artery Occlusion Model Rats
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DOI: 10.1155/2022/8252038
Abstract: According to the ancient documents and Chinese herbal medicine processing experience, Chuanxiong Rhizoma was usually processed with yellow rice wine to improve efficacy. However, the relevant mechanisms are still unclear so far. In this study,… read more here.
Keywords: chuanxiong rhizoma; model rats; rhizoma; middle cerebral ... See more keywords
Pharmacokinetics effects of chuanxiong rhizoma on warfarin in pseudo germ-free rats
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DOI: 10.3389/fphar.2022.1022567
Abstract: Aim: In China, warfarin is usually prescribed with Chuanxiong Rhizoma for treating thromboembolism diseases. However, the reason for their combination is still being determined. The present study explored the pharmacokinetics interactions of warfarin, Chuanxiong Rhizoma,… read more here.
Keywords: chuanxiong rhizoma; pseudo germ; group; germ free ... See more keywords
A Tau Pathogenesis-Based Network Pharmacology Approach for Exploring the Protections of Chuanxiong Rhizoma in Alzheimer’s Disease
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DOI: 10.3389/fphar.2022.877806
Abstract: Alzheimer’s disease (AD) is the most common cause of neurodegenerative dementia and one of the top medical concerns worldwide. Currently, the approved drugs to treat AD are effective only in treating the symptoms, but do… read more here.
Keywords: chuanxiong rhizoma; tau; pharmacology; alzheimer disease ... See more keywords
Anti-Migraine Effect of the Herbal Combination of Chuanxiong Rhizoma and Cyperi Rhizoma and UPLC-MS/MS Method for the Simultaneous Quantification of the Active Constituents in Rat Serum and Cerebral Cortex
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DOI: 10.3390/molecules24122230
Abstract: Chuanxiong Rhizoma and Cyperi Rhizoma (CRCR), an ancient and classic formula comprised of Chuanxiong Rhizoma and Cyperi Rhizoma in a weight ratio of 1:2, has long been used for curing migraine. This study aimed to… read more here.
Keywords: chuanxiong rhizoma; migraine; cyperi rhizoma; active constituents ... See more keywords