Hypoxia-induced angiotensin II by the lactate-chymase-dependent mechanism mediates radioresistance of hypoxic tumor cells
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DOI: 10.1038/srep42396
Abstract: The renin-angiotensin system (RAS) is a principal determinant of arterial blood pressure and fluid and electrolyte balance. RAS component dysregulation was recently found in some malignancies and correlated with poor patient outcomes. However, the exact… read more here.
Keywords: chymase dependent; tumor cells; dependent mechanism; angiotensin ... See more keywords