Modeling Sex Differences in Anti-inflammatory Effects of Dexamethasone in Arthritic Rats
Sign Up to like & getrecommendations! Published in 2018 at "Pharmaceutical Research"
DOI: 10.1007/s11095-018-2483-5
Abstract: PurposeCollagen-induced arthritic (CIA) rats are used commonly for preclinical pharmacologic research into rheumatoid arthritis (RA). Dexamethasone (DEX), a potent corticosteroid (CS), remains an important component in combination therapy for RA. Although sex differences in RA… read more here.
Keywords: differences anti; dex; sex differences; cia rats ... See more keywords
Celastrol attenuates collagen-induced arthritis via inhibiting oxidative stress in rats.
Sign Up to like & getrecommendations! Published in 2020 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2020.106527
Abstract: The present work aimed to investigate the anti-rheumatism effect and the mechanism of celastrol in collagen-induced arthritis (CIA) rats. The CIA model was established in male Wistar rats by intradermal injection of bovine collagen-II in… read more here.
Keywords: induced arthritis; cia rats; celastrol; collagen induced ... See more keywords
The immunosuppressive effects and mechanisms of loureirin B on collagen-induced arthritis in rats
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1094649
Abstract: Introduction Rheumatoid arthritis (RA) is a common disease mainly affecting joints of the hands and wrists. The discovery of autoantibodies in the serum of patients revealed that RA belonged to the autoimmune diseases and laid… read more here.
Keywords: induced arthritis; cell; collagen induced; expression ... See more keywords
Abdominal vagus nerve stimulation alleviates collagen-induced arthritis in rats
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2022.1012133
Abstract: Rheumatoid arthritis (RA) is a chronic, autoimmune inflammatory disease. Despite therapeutic advances, a significant proportion of RA patients are resistant to pharmacological treatment. Stimulation of the cervical vagus nerve is a promising alternative bioelectric neuromodulation… read more here.
Keywords: collagen; vagus nerve; stimulation; cia rats ... See more keywords