Reactive oxygen species scavengers ameliorate mechanical allodynia in a rat model of cancer-induced bone pain
Sign Up to like & getrecommendations! Published in 2018 at "Redox Biology"
DOI: 10.1016/j.redox.2017.10.011
Abstract: Cancer-induced bone pain (CIBP) is a frequent complication in patients suffering from bone metastases. Previous studies have demonstrated a pivotal role of reactive oxygen species (ROS) in inflammatory and neuropathic pain, and ROS scavengers exhibited… read more here.
Keywords: cibp; induced bone; bone; cancer induced ... See more keywords
A Mouse Model of Cancer Induced Bone Pain: From Pain to Movement
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Behavioral Neuroscience"
DOI: 10.3389/fnbeh.2022.873750
Abstract: Cancer induced bone pain (CIBP) occurs in patients with advanced osteosarcoma or metastasized bone tumors that can negatively affects the patient's quality of life. However, motor impairment in CIBP is still understudied. To improve the… read more here.
Keywords: cancer induced; cibp; pain; cancer ... See more keywords
Behavioral Voluntary and Social Bioassays Enabling Identification of Complex and Sex-Dependent Pain-(-Related) Phenotypes in Rats with Bone Cancer
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DOI: 10.3390/cancers15051565
Abstract: Cancer-induced bone pain (CIBP) is a common and devastating symptom with limited treatment options in patients, significantly affecting their quality of life. To uncover the mechanisms underlying CIBP, using rodent models is the most common… read more here.
Keywords: pain related; cibp phenotype; sex; cibp ... See more keywords
Phosphoproteomic profiling of oxycodone‑treated spinal cord of rats with cancer‑induced bone pain.
Sign Up to like & getrecommendations! Published in 2019 at "Molecular medicine reports"
DOI: 10.3892/mmr.2019.10702
Abstract: Treatment of cancer‑induced bone pain (CIBP) is challenging in clinical settings. Oxycodone (OXY) is used to treat CIBP; however, a lack of understanding of the mechanisms underlying CIBP limits the application of OXY. In the… read more here.
Keywords: cibp; induced bone; treated spinal; phosphoproteomic profiling ... See more keywords